Buscar
Mostrando ítems 1-10 de 126
Intrahippocampal Inoculation of Aβ1–42 Peptide in Rat as a Model of Alzheimer’s Disease Identified MicroRNA-146a-5p as Blood Marker with Anti-Inflammatory Function in Astrocyte Cells
(MDPI, 2023)
Circulating microRNAs (miRNAs) have aroused a lot of interest as reliable blood diagnostic biomarkers of Alzheimer's disease (AD). Here, we investigated the panel of expressed blood miRNAs in response to aggregated ...
Análise de microRNAs (miRNAs) em Líquen Plano Bucal
(Universidade Federal de Minas GeraisUFMG, 2011-07-20)
Oral lichen planus (OLP) is a chronic inflammatory disease that is Th1-mediated and affects the oral mucosa with a variety of clinical presentations. Interferon-gamma (IFN-) is an important cytokine involved in the regulation ...
Expression of miRNA-146a, miRNA-155, IL-2, and TNF-alpha in inflammatory response to Helicobacter pylori infection associated with cancer progression
(Wiley, 2018)
miRNAs appear to play an important role in controlling the expression of several genes, and they are a potential biomarker and prognostic tool in gastric diseases. We analyzed 53 controls, 86 patients with gastritis, and ...
MicroRNA miR-146b-5p regulates signal transduction of TGF-beta by repressing SMAD4 in thyroid cancer
(NATURE PUBLISHING GROUPLONDON, 2012)
MicroRNAs (miRNA) are small non-coding RNAs involved in post-transcriptional gene regulation that have crucial roles in several types of tumors, including papillary thyroid carcinoma (PTC). miR-146b-5p is overexpressed in ...
MiRNA-146b-5p upregulates migration and invasion of different Papillary Thyroid Carcinoma cells
(BioMed Central, 2016)
Abstract
Background
Tumor invasiveness is directly related to the ability of tumor cells to migrate and invade surrounding tissues, usually degrading extracellular matrix. ...
Integrative transcriptome analysis identifies deregulated microRNA-transcription factor networks in lung adenocarcinoma
(2016-05-17)
Herein, we aimed at identifying global transcriptome microRNA (miRNA) changes and miRNA target genes in lung adenocarcinoma. Samples were selected as training (N = 24) and independent validation (N = 34) sets. Tissues were ...