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Metastatic melanoma of the tongue: a case report with immunohistochemical profile
(Wiley-Blackwell, 2014-12-01)
BackgroundMelanoma of the skin is characterised by a high metastatic potential, but reports of metastasis to the tongue are rare. We report a case of skin melanoma with metastasis to the lymph nodes, tongue and ...
Metastatic melanoma positively influences pregnancy outcome in a mouse model: could a deadly tumor support embryo life?
(SPRINGER, 2008)
The incidence of melanoma is increasing worldwide. It is one of the leading cancers in pregnancy and the most common malignancy to metastasize to placenta and fetus. There are no publications about experimental models of ...
Metastatic melanoma of the tongue: a case report with immunohistochemical profile
(Wiley-Blackwell, 2015)
Cross-platform comparison of independent datasets identifies an immune signature associated with improved survival in metastatic melanoma
(Impact Journals, 2016-02)
Platform and study differences in prognostic signatures from metastatic melanoma (MM) gene expression reports often hinder consensus arrival. We performed survival/outcome-based pairwise comparisons of three independent ...
Tumor-derived microvesicles modulate the establishment of metastatic melanoma in a phosphatidylserine-dependent manner
(ELSEVIER IRELAND LTD, 2009)
Exposure of phosphatidylserine (PS) on cellular membranes and membrane-derived microvesicles stimulates a number of anti-inflammatory responses involved in malignant processes. Herein we show that B16F10 cells, a highly ...
An inhalable powder formulation based on micro-and nanoparticles containing 5-fluorouracil for the treatment of metastatic melanoma
(2018-02-01)
Melanoma is the most aggressive and lethal type of skin cancer, with a poor prognosis because of the potential for metastatic spread. The aim was to develop innovative powder formulations for the treatment of metastatic ...
Histamine therapeutic efficacy in metastatic melanoma : role of histamine H4 receptor agonists and opportunity for combination with radiation
(Impact Journals, 2017)
Abstract: The aims of the work were to improve our knowledge of the role of H4R in melanoma proliferation and assess in vivo the therapeutic efficacy of histamine, clozapine and JNJ28610244, an H4R agonist, in a preclinical ...
Avaliação da heterogeneidade intratumoral e intermetástases do éxon 15 do gene braf (7q34) em amostras de melanoma metastático
(Universidade Federal de São Paulo (UNIFESP), 2015-06-05)
Introduction: Approximately a half of cutaneous melanoma has a BRAF V600E mutation and benefits from treatment with BRAF and MEK inhibitors, showing rapid tumor regression. However, most of these patients had progression ...