Buscar
Mostrando ítems 1-10 de 84
Memantine prevents cardiomyocytes nuclear size reduction in the left ventricle of rats exposed to cold stress
(Faculdade de Medicina / USP, 2009-01-01)
OBJECTIVES: Memantine is an N-methyl-d-aspartate (NMDA) glutamate receptor antagonist used to treat Alzheimer's disease. Previous studies have suggested that receptor blockers act as neuroprotective agents; however, no ...
Memantine prevents cardiomyocytes nuclear size reduction in the left ventricle of rats exposed to cold stress
(Faculdade de Medicina / USP, 2009)
OBJECTIVES: Memantine is an N-methyl-d-aspartate (NMDA) glutamate receptor antagonist used to treat Alzheimer's disease. Previous studies have suggested that receptor blockers act as neuroprotective agents; however, no ...
Memantine agonist action at dopamine D2High receptors
(Veterinary and Human Toxicology, 2008-02)
Memantine is reported to improve symptoms in moderate cases of Alzheimer´s disease and Parkinson´s disease, but is also known to trigger psychosis in some Parkinson patients. Because these clinical features suggested a ...
The safe, tolerability, and efficacy of once-daily memantine (28mg): a multinational, randomized, placebo-controlled trial in patients with moderate to severe Alzheimer's disease taking cholinesterase inhibitor
(Springer, 2013-06)
INTRODUCTION: Immediate-release memantine (10 mg, twice daily) is approved in the USA for moderate-to-severe Alzheimer's disease (AD). This study evaluated the efficacy, safety, and tolerability of a higher-dose, once-daily, ...
Memantine, an antagonist of the NMDA glutamate receptor, affects cell proliferation, differentiation and the intracellular cycle and induces apoptosis in Trypanosoma cruzi
(Public Library of ScienceSan Francisco, 2014-02-27)
Chagas' disease is caused by the protozoan parasite Trypanosoma cruzi and affects approximately 10 million people in endemic areas of Mexico and Central and South America. Currently available chemotherapies are limited to ...
Determination of memantine in human plasma by liquid chromatography-electrospray tandem mass spectrometry: Application to a bioequivalence study
(Elsevier Science BvAmsterdamHolanda, 2007)