Buscar
Mostrando ítems 1-10 de 18
Polarographic reduction of megazol and derivatives, and its polarographic, UV spectrophotometric, and HPLC determination
(WILEY-V C H VERLAG GMBH, 2001-07)
Megazol (2-amino-5-(1-methyl-5-nitro-2-imidazolyl)-1,3,4-thiadiazol, CAS 19622-55-0), a highly active compound used against several of Trypanosoma cruzi, the causative agent of Chagas disease, is electrochemically studied ...
In vitro and in vivo activities of 1,3,4-thiadiazole-2-arylhydrazone derivatives of megazol against Trypanosoma cruzi
(Antimicrobial Agents and Chemotherapy, 2017)
Mechanism of action of a Nitroimidazole-Thiadiazole derivate upon Trypanosoma cruzi tissue culture amastigotes
(Fundação Oswaldo Cruz. Instituto Oswaldo Cruz., 2020)
Electrochemical study of 4-substituted analogues of megazol
(WILEY-V C H VERLAG GMBH, 2005-02)
The electrochemical behavior of three different megazol analogues substituted at position 4 and their comparison with the parent compound megazol in protic and aprotic media by cyclic voltarnmetry, Tast and differential ...
Cyclic voltammetric studies on nitro radical anion formation from megazol and some related nitroimidazole derivatives
(ELSEVIER SCIENCE B.V., 2001)
Cyclic voltammetric studies on nitro radical anion formation from megazol and some related nitroimidazole derivatives
(ELSEVIER SCIENCE, 2001-09-21)
Megazol (2-amino-5-(1-methyl-5-nitro-2-imdazolyl)-1,3,4-thiadiazol, CAS 19622-55-0) and related nitroimidazole compounds are being tested as antichagasic drugs. Little is known on the mode of action of megazol. However, ...
Nitro radical anions from megazol and related nitroimidazoles in aprotic media. A father-son type reaction triggered by an acidic proton
(PERGAMON-ELSEVIER SCIENCE, 2002-09-25)
We have studied the electrochemical reduction of some nitroimidazoles such as megazol(2-amino-5-(1-methyl-5-nitro-2-imidazolyl)-1,3,4-thiadiazol, CAS 19622-55-0) and two related derivatives in aprotic media (100% DMF, 0.1 ...