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Amifostine does not prevent activation of TGF beta 1 but induces smad 7 activation in megakaryocytes irradiated in vivo
(Wiley-Blackwell, 2002-11-01)
Experiments were undertaken to assess the role of amifostine in the activation of latent TGFbeta1 and in the smad proteins cascade (smad 2/3, smad4, smad7), focusing on megakaryocytes, in the bone marrow irradiated in vivo. ...
Amifostine does not prevent activation of TGF beta 1 but induces smad 7 activation in megakaryocytes irradiated in vivo
(Wiley-Blackwell, 2002-11-01)
Experiments were undertaken to assess the role of amifostine in the activation of latent TGFbeta1 and in the smad proteins cascade (smad 2/3, smad4, smad7), focusing on megakaryocytes, in the bone marrow irradiated in vivo. ...
Measurement of thrombopoietic activity through the quantification of megakaryocytes in bone marrow cytology and reticulated platelets
(Elsevier B.V., 2012-08-01)
Reticulated platelets are considered as marker for bone marrow thrombopoiesis. The aim of the study was evaluate the role of reticulated platelets as markers of thrombopoiesis in dogs. Reticulated platelets analysis by ...
Measurement of thrombopoietic activity through the quantification of megakaryocytes in bone marrow cytology and reticulated platelets
(Elsevier B.V., 2012-08-01)
Reticulated platelets are considered as marker for bone marrow thrombopoiesis. The aim of the study was evaluate the role of reticulated platelets as markers of thrombopoiesis in dogs. Reticulated platelets analysis by ...
Abnormal proplatelet formation and emperipolesis in cultured human megakaryocytes from gray platelet syndrome patients
(Nature Publishing Group, 2016-03)
The Gray Platelet Syndrome (GPS) is a rare inherited bleeding disorder characterized by deficiency ofplatelet α-granules, macrothrombocytopenia and marrow fibrosis. The autosomal recessive form ofGPS is linked to loss of ...
Dysregulation of stromal derived factor 1/CXCR4 axis in the megakaryocytic lineage in essential thrombocythemia
(Wiley Blackwell Publishing, Inc, 2009-01)
This study investigated the involvement of chemokines including stromal derived factor 1 (SDF-1), interleukin 8 (IL-8), growth-related oncogene alpha (GRO-a) and their receptors, CXCR4, CXCR2 and CXCR1 in essential ...
Anagrelide platelet-lowering effect is due to inhibition of both megakaryocyte maturation and proplatelet formation: Insight into potential mechanisms
(Wiley Blackwell Publishing, Inc, 2015-04)
Background and Objectives: Anagrelide represents a treatment option for essential thrombocythemia patients. It lowers platelet counts through inhibition of megakaryocyte maturation and polyploidization, although the basis ...
Semiquantitative assessment of megakaryocytes glycogen for diagnosis idiopathic thrombocytopenic purpuraEvaluación semicuantitativa de glucógeno megacariocítico para el diagnóstico de púrpura trombocitopénica idiopática
(Universidad Nacional Mayor de San Marcos, Facultad de Farmacia y Bioquímica, 2009)
Lectin‑based carbohydrate profile of megakaryocytes in murine fetal liver during development
(Nature Portfolio, 2023)