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EVALUACIÓN DE LA REGULACIÓN TRANSCRIPCIONAL DEL GEN MULTIRESISTENCIA A FÁRMACOS (MDR1) POR EL FACTOR DE TRANSCRIPCIÓN YINYANG 1 (YY1) EN LA LEUCEMIA LINFOBLÁSTICA AGUDA INFANTIL
(2012-03-07)
Introduction. In our country, acute lymphoblastic leukemia (ALL) is the leading cause of
childhood cancer, about 30% of patients do not respond to conventional treatments and do not
survive. One of the most studied ...
Antimicrobial resistance genes and class 1 integrons in MDR Salmonella strains isolated from swine lymph nodes
(2021-10-01)
Food safety is essential to the development of a society, and foodborne diseases affect thousands of people worldwide every year. Among the main foodborne disease agents, Salmonella stands out as the most often associated ...
Differences between nuclear run-off and mRNA levels for multidrug resistance gene expression in the cephalocaudal axis of the mouse Intestine
(ELSEVIER SCIENCE BV, 1995)
P-glycoprotein is a multidrug transporter encoded by the mdr3 gene in the mouse intestinal epithelium. The aims of this study were to characterize the mdr3 gene expression in the cephalocaudal axis of the intestine in adult ...
Cell cycle kinetics, apoptosis rates and gene expressions of MDR-1, TP53, BCL-2 and BAX in transmissible venereal tumour cells and their association with therapy response
(2017-09-01)
Transmissible venereal tumour (TVT) generally presents different degrees of aggressiveness, which makes them unresponsive to conventional treatment protocols. This implies a progressive alteration of their biological ...
Diagnóstico molecular da alteração mutagênica nt 230 (del4) no gene MDR1 em cães
(Universidade Estadual Paulista (Unesp), 2011)
P-glycoprotein is an adenosine triphosphate (ATP)-driven drug efflux carrier responsible for transport of xenobiotics and multiple classes of drugs, many usually use in veterinary medicine. Encoded by MDR1 gene, also ...
Phenotypic and genotypic variant of MDR-Mycobacterium tuberculosis multiple isolates in the same tuberculosis episode, Rio de Janeiro, Brazil
(Associação Brasileira de Divulgação Científica, 2018)
Polimorfismos del gen de resistencia a múltiples drogas (MDR1) en poblaciones chilenas: mapuche, mestiza y maorí
(Sociedad Médica de Santiago, 2004)