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Simulation-based benchmarking of isoform quantification in single-cell RNA-seq
(2018)
Abstract
Single-cell RNA-seq has the potential to facilitate isoform quantification as the confounding factor of a mixed population of cells is eliminated. However, best practice for using existing quantification ...
Structural variants affecting mRNAs isoforms splice sites associated with marbling in Nellore cattle
(Oxford Univ Press Inc, 2020-11-01)
Identification and characterization of an alternatively spliced isoform of the human protein phosphatase 2Aα catalytic subunit
(American Society for Biochemistry and Molecular Biology, 2018)
Splice variants of the human ZC3H14 gene generate multiple isoforms of a zinc finger polyadenosine RNA binding protein
(Elsevier B.V., 2009-06-15)
The human ZC3H14 gene encodes an evolutionarily conserved Cys(3)His zinc finger protein that binds specifically to polyadenosine RNA and is thus postulated to modulate post-transcriptional gene expression. Expressed sequence ...
Identification of novel mRNA isoforms associated with meat tenderness using RNA sequencing data in beef cattle
(2021-03-01)
The Warner-Bratzler shear force (WBSF) and myofibrillar fragmentation index (MFI) are complementary methodologies used to measure beef tenderness. Longissimus thoracis samples from the 20 most extreme bulls (out of 80 bulls ...
Small genetic variation affecting mRNA isoforms associated with marbling and meat color in beef cattle
(2022-01-01)
The aim of this study was to identify mRNA isoforms and small genetic variants that may be affecting marbling and beef color in Nellore cattle. Longissimus thoracis muscle samples from 20 bulls with different phenotypes ...
The use of alternative polyadenylation sites renders β1- integrin mRNA isoforms with differential stability during mammary gland development
(Portland Press, 2013-09)
Integrins are heterodimeric cell-surface adhesion receptors that play a critical role in tissue development. Characterization of the full-length mRNA encoding the β1 subunit (Itgb1) revealed an alternative functional ...
Identification and characterization of proteins that selectively interact with isoforms of the mRNA binding protein AUF1 (hnRNP D)
(Walter De Gruyter & CoBerlinAlemanha, 2003)
A benchmarking of workflows for detecting differential splicing and differential expression at isoform level in human RNA-seq studies
(Oxford University Press, 2017-10)
Over the last few years, RNA-seq has been used to study alterations in alternative splicing related to several diseases. Bioinformatics workflows used to perform these studies can be divided into two groups, those finding ...