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3 SUBTYPES OF ALPHA-BUNGAROTOXIN SENSITIVE NICOTINIC ACETYLCHOLINE-RECEPTORS ARE EXPRESSED IN CHICK RETINA
(Soc Neuroscience, 1993-02-01)
A recent report described the isolation of cDNA clones encoding alpha7 and alpha8 subunits of alpha-bungarotoxin-sensitive nicotinic ACh receptors (alphaBgtAChRs) from chick brain and demonstrated that they were related ...
Estudio de la interacción lípido-proteína sobre la función y la organización del receptor de acetilcolina nicotínico en membranas y en sistemas modelos simples
(2014-12-16)
En esta Tesis doctoral se profundizó en el estudio de la interacción lípido-receptor de acetilcolina nicotínico (AChR) en dos aspectos: por un lado, el mecanismo de inhibición de ácidos grasos libres (AGLs), antagonistas ...
Readthrough acetylcholinesterase (AChE-R) and regulated necrosis: pharmacological targets for the regulation of ovarian functions?
(Nature, 2015)
Proliferation, differentiation and death of ovarian cells ensure orderly functioning of the female gonad during the reproductive
phase, which ultimately ends with menopause in women. These processes are regulated by several ...
Readthrough acetylcholinesterase (AChE-R) and regulated necrosis: pharmacological targets for the regulation of ovarian functions?
(Nature, 2015)
Proliferation, differentiation and death of ovarian cells ensure orderly functioning of the female gonad during the reproductive
phase, which ultimately ends with menopause in women. These processes are regulated by several ...
All you need is coffe
(Fundación Revista Medicina, 2017)
Cholinergic deficit is regarded as an important factor responsible for Alzheimer’s disease symptoms. Two molecular targets for the treatment of this disease are acetylcholinesterase (AChE) and nic otinic receptor (nAChR). ...
A conserved arginine with non‐conserved function is a key determinant of agonist selectivity in α7 nicotinic ACh receptors
(Wiley Blackwell Publishing, Inc, 2021-04)
The α7 and α4β2* (“*” denotes possibly assembly with another subunit) nicotinic acetylcholine receptors (nAChRs) are the most abundant nAChRs in the mammalian brain. These receptors are the most targeted nAChRs in drug ...
Avaliação da expressão gênica e proteica dos receptores nicotínicos em modelo in vitro de infecção por SARS-CoV-2 com e sem superexpressão de ECA2
(Universidade Federal de São Paulo, 2023-02-27)
Introdução: O SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) é o vírus causador da COVID-19 (Coronavírus disease 2019), doença decretada pandêmica em 2020. A entrada do vírus na célula hospedeira ocorre após ...
Contribution of subunits to Caenorhabditis elegans levamisole-sensitive nicotinic receptor function
(American Society for Pharmacology and Experimental Therapeutics, 2012-09-25)
Caenorhabditis elegans muscle contains seven different nicotinic receptor (AChR) subunits, five of which have been shown to be components of adult levamisole-sensitive AChRs (L-AChRs). To elucidate the reason for such ...