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Eficacia del lumiracoxib e ibuprofeno en el tratamiento del dolor postoperatorio en la exodoncia de terceros molares
(Universidad de Talca (Chile). Escuela de Odontologia., 2009)
Lumiracoxib for acute postoperative dental pain: a systematic review of randomized clinical trials
(Associação Paulista de Medicina - APM, 2011-01-01)
CONTEXT AND OBJECTIVE: Lumiracoxib is an anti-inflammatory drug that has been used to treat acute dental pain, mainly in postsurgical settings, in which the greatest levels of pain and discomfort are experienced during the ...
Efeito do inibidor da cox-2 lumiracoxibe, do anti-tnf-α etanercepte e da sua associação, na colite induzida pelo 2,4,6-ácido trinitrobenzeno-sulfônico em ratos
(Universidade Federal de São Paulo (UNIFESP), 2010-07-28)
Aim: The present study aimed to evaluate the effect of lumiracoxib, a selectivecyclooxygenase- 2 (COX-2) inhibitor, and etanercept (ETC), a tumour necrosis factor alpha (TNF-α) antagonist, and the association of both drugs ...
Interacción Sinérgica entre la Lidocaína y Lumiracoxib en la prueba de formalina 1% en ratas
(2011)
It has been shown that the association of non-steroidal anti-inflammatory drugs (NSAIDs)
with analgesic agents can increase their antinociceptive activity, allowing the use of lower
doses and thus limiting side effects. ...
Effect of COX-2 inhibitor after TNBS-induced colitis in wistar rats
(Springer, 2009-08-01)
Inflammatory bowel disease (IBD) is a common chronic gastrointestinal disorder characterized by alternating periods of remission and active intestinal inflammation. Some studies suggest that antiinflammatory drugs are a ...
Synthesis, Characterization and Pharmacological Evaluation of 1-(2-Chloro-6-Fluorophenyl)-5-Methylindolin-2-One: A New Anti-Inflammatory Compound with Reduced Gastric Ulceration Properties
(Mdpi Ag, 2010-11-01)
The new compound 1-(2-chloro-6-fluorophenyl)-5-methylindolin-2-one (1), designed using the prodrug approach, was easily obtained in 85% yield and characterized by nuclear magnetic resonance, elemental analysis, mass ...
Synthesis, Characterization and Pharmacological Evaluation of 1-(2-Chloro-6-Fluorophenyl)-5-Methylindolin-2-One: A New Anti-Inflammatory Compound with Reduced Gastric Ulceration Properties
(Mdpi Ag, 2010-11-01)
The new compound 1-(2-chloro-6-fluorophenyl)-5-methylindolin-2-one (1), designed using the prodrug approach, was easily obtained in 85% yield and characterized by nuclear magnetic resonance, elemental analysis, mass ...
Pharmacokinetic pharmacodynamic modelling of the analgesic effects of lumiracoxib, a selective inhibitor of cyclooxygenase-2, in ratsbph
(2010)
This study establishes a pharmacokinetic/pharmacodynamic (PK/PD) model to describe the time course and in vivo mechanisms of action of the antinociceptive effects of lumiracoxib, evaluated by the thermal hyperalgesia test in rats.