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Collaborative care models to address late-life depression: Lessons for low-and-middle-income countries
(Frontiers Research Foundation, 2015)
Psychiatry: life events and social support in late life depression
(Faculdade de Medicina / USP, 2011)
OBJECTIVES: To examine the association of life events and social support in the broadly defined category of depression in late life. INTRODUCTION: Negative life events and lack of social support are associated with depression ...
Platelet GSK3B activity in patients with late-life depression: Marker of depressive episode severity and cognitive impairment?
(INFORMA HEALTHCARE, 2011)
Objective. Increased GSK3B activity has been reported as a state marker of major affective episodes in patients with depression and bipolar disorder. No study so far has addressed GSK3B activity in late-life depression. ...
Increased soluble TNF receptor 2 in antidepressant-free patients with late-life depression
(PERGAMON-ELSEVIER SCIENCE LTD, 2010)
Increased pro-inflammatory state has been implicated in the pathophysiology of major depressive disorder. The aim of this study was to determine serum levels of INF-alpha and soluble TNF-alpha receptors 1 and 2 (sTNFR1 and ...
A comparative cross-cultural study of the prevalence of late life depression in low and middle income countries
(Elsevier, 2016)
Background: Current estimates of the prevalence of depression in later life mostly arise from studies carried out in Europe, North America and Asia. In this study we aimed to measure the prevalence of depression using a ...
Serum brain-derived neurotrophic factor level is reduced in antidepressant-free patients with late-life depression
(TAYLOR & FRANCIS LTD, 2010)
Objectives. The aim of the present study is to investigate serum BDNF levels in older depressed patients as compared to healthy elderly controls. Methods. Twenty-nine elderly subjects with major depression and 42 healthy ...
Cognitive impairment in remitted late-life depression is not associated with Alzheimer's disease-related CSF biomarkers
(2020-07-01)
Background: Cognitive impairment is a common feature of late-life depression (LLD). Early studies using Alzheimer's disease (AD) biomarkers inferred a biological link between AD pathology and LLD, but recent findings have ...
Risk factors for suicidal behaviour in late-life depression: A systematic review
BACKGROUND
Suicide is a leading cause of preventable death worldwide, with its peak of maximum incidence in later life. Depression often puts an individual at higher risk for suicidal behaviour. In turn, depression deserves ...
Perfil clínico de depresión vascular
(Universidad Católica de Pereira, 2011-04-06)
La población de adultos mayores y ancianos aumenta constantemente y con ello aumenta la prevalencia de entidades como depresión y ECV. Se ha planteado que la depresión en los adultos mayores y ancianos tiene características ...
Circulating Glial-derived neurotrophic factor is reduced in late-life depression
(PERGAMON-ELSEVIER SCIENCE LTDOXFORD, 2012)
Background: The Glial Cell-line derived neurotrophic factor (GDNF) is part of the TGF-beta superfamily and is abundantly expressed in the central nervous system. Changes in GDNF homeostasis have been reported in affective ...