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Lamotrigine as a mood stabilizer: insights from the pre-clinical evidence
(Universidade Federal de Minas GeraisBrasilICB - DEPARTAMENTO DE MORFOLOGIAICX - DEPARTAMENTO DE QUÍMICAMED - DEPARTAMENTO DE CLÍNICA MÉDICAUFMG, 2019)
Neuroprotective effects of oral lamotrigine administration on rabbit retinas after pars plana vitrectomy and silicone oil injection
(LIPPINCOTT WILLIAMS & WILKINS, 2008)
Purpose: To investigate potential retinal neuroprotective effects of oral lamotrigine in rabbits after pars plana vitrectomy (PPV) and intravitreal silicone oil injection (SOI). Methods: Twelve New Zealand rabbits (weight, ...
Interchangeability among therapeutics equivalents of lamotrigine in the treatment of refractory epilepsy patients: risks and benefits
(REVISTA DE NEUROLOGIA, 2010)
Introduction. Epilepsy is a condition characterized by signs and symptoms of neurological disorder. Lamotrigine has been widely used, mainly due to their greater tolerability and lower rate of drug interactions with other ...
Interchangeability among therapeutic equivalents of lamotrigine: evaluation of quality of life
(UNIV SAO PAULO, CONJUNTO QUIMICASSAO PAULO, 2012)
Epilepsy is the most common serious neurological disorder worldwide. Approximately 70% of patients with epilepsy have their seizures controlled by clinical and pharmacological treatment. This research evaluated the possible ...
Interchangeability among therapeutic equivalents of lamotrigine: evaluation of quality of life
(Universidade de São Paulo, Faculdade de Ciências Farmacêuticas, 2012)
Epilepsy is the most common serious neurological disorder worldwide. Approximately 70% of patients with epilepsy have their seizures controlled by clinical and pharmacological treatment. This research evaluated the possible ...
What are the comparative effects of ethosuximide, sodium valproate, or lamotrigine for children and adolescents with absence seizures?
(Cochrane Clinical Answers, 2019-10-07)
For children and adolescents with absence seizures, there was little or no evidence of a difference in outcomes between ethosuximide and valproate. However, lamotrigine was less effective than other treatments; fewer ...
Hydrogen-bonding synthons in lamotrigine salts: 3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazin-2-ium 2-[(2-carboxyphenyl)disulfanyl]benzoate in its monohydrate and anhydrous forms
(International Union of Crystallography, 2016-10)
Lamotrigine is a drug used in the treatment of epilepsy and related convulsive diseases. The drug in its free form is rather inadequate for pharmacological use due to poor absorption by the patient, which limits its ...
Lamotrigine-induced toxic epidermal necrolysis treated with intravenous immunoglobulin and amniotic membranes
(AMER MEDICAL ASSOC, 2008-06)
Late Adverse Effects of the Coadministration of Valproate and Lamotrigine
(ELSEVIER SCIENCE INCNEW YORK, 2012)
Individuals treated with combined valproate-lamotrigine rarely present late adverse effects (unrelated to introduction and titration). We describe four patients in whom such effects occurred after continuous, long-term use ...