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Multiple gene knock-down by a single lentiviral vector expressing an array of short hairpin RNAs
(Pontificia Universidad Católica de Valparaíso, 2006)
CRISPR-Cas13d Induces Efficient mRNA Knockdown in Animal Embryos
(Elsevier, 2020)
The development of mRNA knockdown technologies for use in vertebrate organisms such as zebrafish has been limited. Kushawah et al. establish CRISPR-RfxCas13d as an efficient, specific, cost-effective, and straightforward ...
Mating success at high temperature in highland- and lowland-derived populations as well as in heat knock-down selected Drosophila buzzatii
(Wiley Blackwell Publishing, Inc, 2015-03)
Thermal-stress selection can affect multiple fitness components including mating success. Reproductive success is one of the most inclusive measures of overall fitness, and mating success is a major component of reproduction. ...
Data of H2O2 release from AQP8-knockdown rat hepatocyte mitochondria
(Elsevier, 2021)
Resistência "knockdown" em mosquitos Aedes aegypti no Brasil e suas implicações no controle da dengue
(Universidade Federal de São CarlosUFSCarCâmpus ArarasCiências Biológicas - CBL-Ar, 2021-04-16)
Dengue is an arbovirus that, since its introduction, represents a great problematic for world public health, mainly in Brazil, which presents a great difficulty in eradicating this disease. Its main vector, Aedes aegypti ...
Hydrogen peroxide and Helicobacter pylori extract treatment combined with APE1 knockdown induce DNA damage, G2/M arrest and cell death in gastric cancer cell line
(2020-12-01)
Chronic inflammation resulting from Helicobacter pylori (H. pylori) infection, the major risk factor for gastric cancer, results in increased release of reactive oxygen species (ROS), promoting oxidative stress and DNA ...
Immunotherapy for breast cancer using EpCAM aptamer tumor-targeted gene knockdown
(National Academy of Sciences, 2022)
Evidence for necrosis, but not apoptosis, in human hepatoma cells with knockdown of mitochondrial aquaporin-8
(Springer, 2014-01)
We previously found that mitochondrial aquaporin-8 (mtAQP8) channels facilitate mitochondrial H2O2 release in human hepatoma HepG2 cells and that their knockdown causes oxidant-induced mitochondrial dysfunction and loss ...