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From yeast killer toxins to antibiobodies and beyond
(Wiley-Blackwell, 2008-11-01)
Antibiobodies are paradigmatic of yeast killer toxin (KT)-like antibodies (KAbs) mimicking the antimicrobial activity of KTs in the frame of the yeast killer phenomenon. Polyclonal, monoclonal and recombinant anti-idiotypic ...
Antifungal and antitumor models of bioactive protective peptides
(Academia Brasileira de Ciências, 2009-09-01)
Peptides are remarkably reactive molecules produced by a great variety of species and able to display a number of functions in uni-and multicellular organisms as mediators, agonists and regulating substances. Some of them ...
Role of natural killer cells in antitumor resistance
(2005-12-01)
Natural killer cells constitute a population of lymphocytes able to non-specifically destroy virus-infected and some kinds of tumor cells. Since this lytic activity was shown by non-immunized animals the phenomenon is ...
Enhancement of human natural killer cell activity by opioid peptides: Similar response to methionine-enkephalin and β-endorphin
(1992)
We studied the effect of methionine-enkephalin (MET) and β-endorphin upon human peripheral blood lymphocyte natural killer cell (NKC) activity in a group of healthy volunteers (n = 27; 17 male and 10 female, age ± SD and ...
Natural killer cells as helper cells in dendritic cell cancer vaccines
(Frontiers Research Foundation, 2015-01)
Vaccine-based cancer immunotherapy has generated highly variable clinical results due to differing methods of vaccine preparation and variation in patient populations among other lesser factors. Moreover, these clinical ...
Killer lymphocytes use granulysin, perforin and granzymes to kill intracellular parasites.
(Nature Publishing Company, 2016)
Role of natural killer cells in antitumor resistance
(2005-12-01)
Natural killer cells constitute a population of lymphocytes able to non-specifically destroy virus-infected and some kinds of tumor cells. Since this lytic activity was shown by non-immunized animals the phenomenon is ...
The immunophenotype of amniotic fluid leukocytes in normal and complicated pregnancies
(WILEY, 2018)
ProblemThe immune cellular composition of amniotic fluid is poorly understood. Herein, we determined: 1) the immunophenotype of amniotic fluid immune cells during the second and third trimester in the absence of intra-amniotic ...
Analogues of Human Granulysin as Antimycobacterial Agents
(Springer, 2019-06)
Antimicrobial peptides are essential components of innate defense mechanisms and make promising candidates for novel anti-infective agents. The advantages of these peptides in clinical applications include their potential ...