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The role of myofibroblasts and interstitial fibrosis in the progression of membranous nephropathy
(2004-09-15)
Renal interstitial fibrosis has been observed in a large number of nephropathies and contributes to the progressive deterioration of renal function. Myofibroblasts have been implicated in the reparative process of tissue ...
The role of myofibroblasts and interstitial fibrosis in the progression of membranous nephropathy
(2004-09-15)
Renal interstitial fibrosis has been observed in a large number of nephropathies and contributes to the progressive deterioration of renal function. Myofibroblasts have been implicated in the reparative process of tissue ...
Reticulin antibodies: relationship with endocardium-vessel-interstitium antibodies and heterophilic antibodies.
(1990-01-01)
1. Indirect immunofluorescence was used to compare reticulin antibodies, endocardium-vessel-interstitium (EVI) antibodies and heterophilic antibodies in serum samples from patients with degenerative and inflammatory diseases, ...
NF-κB activation mediates crystal translocation and interstitial inflammation in adenine overload nephropathy
(American Physiological SocietyBethesda, 2013-07-15)
Adenine overload promotes intratubular crystal precipitation and interstitial nephritis. We showed recently that these abnormalities are strongly attenuated in mice knockout for Toll-like receptors-2, -4, MyD88, ASC, or ...
Pathogenesis of Fabry nephropathy: The pathways leading to fibrosis
(Academic Press Inc Elsevier Science, 2020-02)
Background: Kidney is one of the main target organs in Fabry disease, a lysosomal X-linked genetic disorder. Renal involvement is characterized by proteinuria and progressive chronic kidney disease leading to end-stage ...
Intrarenal renin-angiotensin system is upregulated in experimental model of progressive renal disease induced by chronic inhibition of nitric oxide synthesis
(Lippincott Williams & Wilkins, 2004-07-01)
Locally generated angiotensin II (AngII) may be involved in the pathogenic mechanisms of chronic renal diseases. Renal expression of AngII and other components of the renin-angiotensin system (RAS) were analyzed by ...
Total hepatic ischemia and reperfusion after state controlled hemorrhagic shock, with used of different solutions: effects of neutrophils sequestration in kidney of ratsIsquemia e reperfusão hepática total após estado de choque hemorrágico controlado com uso de diferentes soluções: efeitos no seqüestro de neutrófilos no rim de ratos
(Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2006)
Ang-(3-4) suppresses inhibition of renal plasma membrane calcium pump by Ang II
(Elsevier B.V., 2009-06-05)
We previously demonstrated that Ang II inhibits the renal plasma membrane Ca(2+)-ATPase. in the present work we have studied the effect of Ang II, at concentrations similar to those found in the renal interstitium, on the ...