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Hepatic Nrf2 expression is altered by quercetin supplementation in X.irradiated rats
(Spandidos Publications, 2015)
Análisis de la actividad del factor de transcripción Nrf2 en células HEK293 estimuladas con péptidos IDR
(Universidad Michoacana de San Nicolás de Hidalgo, 2018-08)
Oxidative stress refers to a condition in which the concentration of reactive oxygen species (ROS) surpasses the capacity of antioxidant cellular defenses. This causes alterations in the structure and function of biomolecules ...
Nrf2 activation in the liver of rats subjected to a preconditioning sub-chronic iron protocol
(2014)
Sub-chronic iron (Fe) administration induces liver oxidative stress upregulating cytoprotective mechanisms that may involve redox-sensitive nuclear factor erythroid 2-related factor 2 (Nrf2). We aimed to investigate whether ...
Exercise Prevents Diaphragm Wasting Induced by Cigarette Smoke through Modulation of Antioxidant Genes and Metalloproteinases
(Hindawi Ltd, 2018)
Background. The present study aimed to analyze the effects of physical training on an antioxidant canonical pathway and metalloproteinases activity in diaphragm muscle in a model of cigarette smoke-induced chronic obstructive ...
Efecto del estrés crónico emocional sobre la regulación de la expresión y actividad de NRF2 en el hipocampo ventral de ratas macho y hembra
(Universidad de Chile, 2022)
Los estudios epidemiológicos han demostrado que las mujeres tienen una mayor incidencia de trastornos del estado de ánimo, como ansiedad y depresión mayor, que los hombres. Ambos trastornos están asociados con el estrés, ...
The use of antioxidants as potential co-adjuvants to treat chronic chagas disease
(MDPI, 2021)
Chagas disease is a neglected tropical disease caused by the flagellated protozoa Trypanosome cruzi. This illness affects to almost 8-12 million people worldwide, however, is endemic to Latin American countries. It is ...
Theoretical Study of the Antioxidant Activity of Quercetin Oxidation Products
(Frontiers Media S.A., 2019-11)
It was recently shown that, when tested in cellular systems, quercetin oxidized products (Qox) have significantly better antioxidant activity than quercetin (Q) itself. The main Qox identified in the experiments are either ...
NFE2-Related transcription factor 2 coordinates antioxidant defense with thyroglobulin production and iodination in the thyroid gland
(Mary Ann Liebert, 2018-06)
Background: The thyroid gland has a special relationship with oxidative stress. While generation of oxidative substances is part of normal iodide metabolism during thyroid hormone synthesis, the gland must also defend ...
A via Nrf2 participa da maior modulação endotelial induzida pela prenhez sobre reatividade de aortas à fenilefrina.
(Universidade Estadual Paulista (Unesp), 2020-09-08)
Alterações em diferentes vias de sinalização levam a disfunção vascular e endotelial e consequentemente a hipertensão. A hipertensão está relacionada diretamente com o aumento da produção de espécies reativas de oxigênio ...