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Racemized and Isomerized Proteins in Aging Rat Teeth and Eye Lens
(Mary Ann Liebert, 2016-08)
The quantification of aspartic acid racemization in the proteins of nonmetabolically active tissues can be used as a measure of chronological aging in humans and other long-lived organisms. However, very few studies have ...
It's all about tau
(Elsevier Ltd, 2019)
Minute time scale prolyl isomerization governs antibody recognition of an intrinsically disordered immunodominant epitope
(American Society For Biochemistry And Molecular Biology, 2013-03)
Conformational rearrangements in antibody·antigen recognition are essential events where kinetic discrimination of isomers expands the universe of combinations. We investigated the interaction mechanism of a monoclonal ...
An examination of the involvement of proline peptide isomerization in protein folding
(1978)
The proline peptide isomerization model of protein folding predicts that the fraction of denatured polypeptide chains which rapidly fold should be quantitatively related to the numbers of cis and trans proline residues in ...
Protein interacting with NIMA (never in mitosis A)-1 regulates axonal growth cone adhesion and spreading through myristoylated alanine-rich C kinase substrate isomerization
(Wiley Blackwell Publishing, Inc, 2016-06)
Axonal growth cone motility requires precise regulation of adhesion to navigate the complex environment of the nervous system and reach its target. Myristoylated alanine-rich C kinase substrate (MARCKS) protein is enriched ...
Chemometric modeling of the electrochemical data to investigate proline cis/trans isomeration effect on aggregation of Tau protein
(Elsevier, 2021-06)
Tau protein (Tau) is a proline-rich protein and in this work, we have developed a very interesting strategy based on combination of electrochemistry with chemometric methods to investigate proline cis/trans isomeration ...