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Lindane‐induced liver oxidative stress: Respiratory alterations and the effect of desferrioxamine in the isolated perfused rat liver
(1989)
The effects of lindane administration (25–60 mg kg−1 for 24 h) on hepatic oxygen consumption were studied in the isolated perfused rat liver, in the absence and presence of the iron‐chelator free‐radical scavenger ...
Uptake of dodecanedioic acid by isolated rat liver
(ELSEVIER SCIENCE BV, 1997)
The uptake of dodecanedioic acid (C12), a dicarboxylic acid with 12 carbon atoms, was studied in the isolated perfused rat liver. Fifty pmol of C12 were injected as a bolus into the perfusing liver solution. The concentration ...
Pharmacokinetics and hepatotoxicity of diclofenac using an isolated perfused rat liver
(EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 1997)
Pharmacokinetics and hepatotoxicity of diclofenac was studied in a recirculating model of isolated perfused rat liver. Ten male Sprague-Dawley rat (weighing 230-330 g) livers were perfused for 2 h with 250 mt Krebs-Henseleit ...
Portal hypertensive response to bradykinin in inflamed or cirrhotic rat livers is mediated by B-2-type receptors
(Blackwell Science Asia, 2001-01-01)
Background: We have shown that the portal hypertensive response to bradykinin in normal rats is mediated by B-2 receptors.Methods: By using isolated and exsanguinated rat liver perfusion, we studied the portal hypertensive ...
Vanillin suppresses kupffer cell-related colloidal carbon-induced respiratory burst activity in isolated perfused rat liver: anti-inflammatory implications
(THE ROYAL SOCIETY OF CHEMISTRY, 2012)
Effect of thyroid hormone administration on the depletion of circulating glutathione in the isolated perfused rat liver and its relationship to basolateral γ‐glutamyltransferase activity
(1995)
The influence of thyroid hormone administration on liver glutathione (GSH) extraction in the isolated perfused liver was studied in fed rats for a period of 1–7 days following a single dose of 0.1 mg 3,5,3′‐triiodothyronine ...
The disposition of nifurtimox in the rat isolated perfused liver: effect of dose size
(1993)
Abstract— The disposition of nifurtimox was studied in the rat isolated perfused liver using a recirculating system. The drug was administered as a bolus (5·0, 15·0 or 30·0 μg mL−1), and its disappearance was monitored by ...
3,3',5-Triiodothyronine-induced hepatic respiration: Effects of desferrioxamine and allopurinol in the isolated perfused rat liver
(1993)
The effect of daily doses of 0.1 mg 3,3',5-triiodothyronine (T3) kg for three consecutive days on hepatic O2 uptake was studied in the isolated perfused rat liver, in the absence and presence of the antioxidants desferrioxamine ...
Disposition of Nifurtimox and Metabolite Activity Against Trypanosoma cruzi using Rat Isolated Perfused Liver
(1994)
Abstract— Nifurtimox disposition was investigated using the rat isolated perfused‐liver method after administration of 25 μg mL−1 nifurtimox, and its disappearance was monitored by analysing the perfusate sample at various ...