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Endothelium-dependent coronary flow in ischemia reperfusion
(Gustav Fischer VerlagJenaAlemanha, 1997)
Insulin/NFκB protects against ischemia-induced necrotic cardiomyocyte death
(Academic Press Inc., 2015)
In the heart, insulin controls key functions such as metabolism, muscle contraction and cell death. However, all studies have been focused on insulin action during reperfusion. Here we explore the cardioprotective action ...
CaMKII-dependent responses to ischemia and reperfusion challenges in the heart
(Frontiers, 2014-05)
Ischemic heart disease is a leading cause of death, and there is considerable imperative to identify effective therapeutic interventions. Cardiomyocyte Ca2+ overload is a major cause of ischemia and reperfusion injury, ...
Potential Therapies to Protect the Aging Heart Against Ischemia/Reperfusion Injury
(Frontiers Media, 2021)
Despite important advances in the treatment of myocardial infarction that have significantly reduced mortality, there is still an unmet need to limit the infarct size after reperfusion injury in order to prevent the onset ...
Nicorandil protects cardiac mitochondria against permeability transition induced by ischemia-reperfusion
(SPRINGER/PLENUM PUBLISHERS, 2008)
Ischemia followed by reperfusion is known to negatively affect mitochondrial function by inducing a deleterious condition termed mitochondrial permeability transition. Mitochondrial permeability transition is triggered by ...
A novel electrophysiologic effect of melatonin on ischemia/reperfusion- induced arrhythmias in isolated rat hearts
(Wiley Blackwell Publishing, Inc, 2009-03)
Reperfusion after a short period of cardiac ischemia triggers ventricular arrhythmias attributable to ionic imbalance and oxidative stress. Melatonin offers some degree of protection, but its effects on the cardiac action ...