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Challenges of the intensive insulin therapy in experimental models of extensive burn injury
(World Journal Series, 2020-08-30)
Análogos de insulina: en búsqueda del reemplazo fisiológico
(Sociedad Médica de Santiago, 2006)
Insulin analogues: Searching for a physiological replacement Análoges de insulina: En búsqueda del reemplazo fisiológico
(2006)
Insulin analogues, developed by molecular engineering, have structural changes in the A and B insulin chains. These modifications change their action profile, rendering insulin replacement closer to physiology. Rapid acting ...
Islet adaptive changes to fructose-induced insulin resistance: β-cell mass, glucokinase, glucose metabolism, and insulin secretion
(BioScientifica, 2009-02)
β-Cell mass, hexokinase/glucokinase (HK/GK) activity, glucose metabolism and insulin secretion were studied in the islets of rats with fructose-induced insulin resistance (IR). Normal male Wistar rats were fed a standard ...
Role of Islet Glucokinase, Glucose Metabolism, and Insulin Pathway in the Enhancing Effect of Islet Neogenesis-Associated Protein on Glucose-Induced Insulin Secretion
(Lippincott Williams, 2015-08)
Objective: To demonstrate the role of islet glucokinase, glucose metabolism, and intracellular insulin mediators in the enhancing effect of islet neogenesis-associated protein pentadecapeptide (INGAP-PP) on glucoseinduced ...
Subclinical abnormalities of glucose metabolism in Brazilian women with a history of gestational diabetes mellitus
(Blackwell Munksgaard, 2004-12-01)
Background. To evaluate insulin release and insulin sensitivity in women with prior gestational diabetes mellitus (GDM) to gain a better understanding of type 2 diabetes pathogenesis.Methods. GDM women were individually ...
Subclinical abnormalities of glucose metabolism in Brazilian women with a history of gestational diabetes mellitus
(Blackwell Munksgaard, 2004-12-01)
Background. To evaluate insulin release and insulin sensitivity in women with prior gestational diabetes mellitus (GDM) to gain a better understanding of type 2 diabetes pathogenesis.Methods. GDM women were individually ...
Anthropometric measurements for assessing insulin sensitivity on patients with metabolic syndrome, sedentaries and marathoners
(INSTITUTE OF ELECTRICAL AND ELECTRONICS ENGINEERS INC., 2015-08-25)
The diagnosis of low insulin sensitivity is commonly done through the HOMA-IR index, in which fasting insulin and glucose blood levels are evaluated. Insulin and blood glucose levels are used for insulin sensitivity ...
Moderate physical activity from childhood contributes to metabolic health and reduces hepatic fat accumulation in adult rats
(2013-03-08)
Background: Obesity, oxidative stress and inflammation, by triggering insulin resistance, may contribute to the accumulation of hepatic fat, and this accumulation by lipotoxicity can lead the organ to fail. Because obesity ...
Moderate physical activity from childhood contributes to metabolic health and reduces hepatic fat accumulation in adult rats
(2013-03-08)
Background: Obesity, oxidative stress and inflammation, by triggering insulin resistance, may contribute to the accumulation of hepatic fat, and this accumulation by lipotoxicity can lead the organ to fail. Because obesity ...