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Analysis of the biorelevance of the main methods used to compare in vitro dissolution profiles
(CompareNetworks, 2013-12)
The article analyzes comparatively the performance of the main methods proposed for the comparison of percent dissolved vs. time curves: model-dependent, model-independent and ANOVA-based statistical methods. In particular, ...
Development and validation of a dissolution test for diltiazem hydrochloride in immediate release capsules
(Sociedade Brasileira de Química, 2011-01-01)
This work describes the development and validation of a dissolution test for 60 mg of diltiazem hydrochloride in immediate release capsules. The best dissolution in vitro profile was achieved using potassium phosphate ...
Development and validation of a dissolution test for diltiazem hydrochloride in immediate release capsules
(Sociedade Brasileira de Química, 2011-01-01)
This work describes the development and validation of a dissolution test for 60 mg of diltiazem hydrochloride in immediate release capsules. The best dissolution in vitro profile was achieved using potassium phosphate ...
Albendazole Solid Dispersions: Influence of Dissolution Medium Composition on In Vitro Drug Release
(Dissolution Technologies, Inc, 2014-01)
The rate-limiting step to drug absorption is often dissolution from the dosage form, especially for poorly soluble com-pounds. Two possibilities for improving the dissolution of these drugs are to increase the available ...
Solid dispersions containing Albendazole: Influence of dissolution media composition on in vitro drug release
(Dissolution Technologies, Inc, 2014-05)
The rate-limiting step to drug absorption is often dissolution from the dosage form, especially for poorly soluble com-pounds. Two possibilities for improving the dissolution of these drugs are to increase the available ...
Analysis of bovine pulp tissue dissolution ability by photodynamic therapy: an in vitro studyAnálise da capacidade de dissolução de tecido pulpar bovino através da terapia fotodinâmica: estudo in vitro
(EDIPUCRSPorto Alegre, 2011)
Purpose: To evaluate the bovine pulp tissue dissolution ability of photodynamic therapy. Methods: Twenty pieces of bovine pulp tissue were weighed and divided randomly into four groups (n=5), according to the cleaning ...
Analysis of bovine pulp tissue dissolution ability by photodynamic therapy: an in vitro studyAnálise da capacidade de dissolução de tecido pulpar bovino através da terapia fotodinâmica: estudo in vitro
(EDIPUCRSPorto Alegre, 2011)
Purpose: To evaluate the bovine pulp tissue dissolution ability of photodynamic therapy. Methods: Twenty pieces of bovine pulp tissue were weighed and divided randomly into four groups (n=5), according to the cleaning ...
Intrinsic dissolution simulation of highly and poorly soluble drugs for BCS solubility classification
(Dissolution Technologies, Inc, 2017)
Intrinsic dissolution testing allows characterizing drug substances through its dissolution rate when exposed to a specified surface area in a specific dissolution media, This can be used to determine if a drug substance ...