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Current knowledge of immunosuppression as a risk factor for skin cancer development
(2022)
This review outlines our current understanding of the relationship between immunosuppression and skin cancer.
Primary immunodeficiencies increase the incidence of skin cancer, but due to their low frequency, the establishment ...
Clinical Pharmacology and Therapeutic Drug Monitoring of Immunosuppressive Agents
(2013)
Immunosuppressive drugs are used to reduce the immune response in organ transplantation and autoimmune disease. The pharmacokinetics of the immunosuppressive drugs is complex and unpredictable. Therapeutic drug monitoring ...
Immunosuppression and malignant neoplasms: Risk-benefit assessment in patients with inflammatory bowel disease
(2020-01-01)
Objective: Adverse events of drug therapy Background: The treatment of inflammatory bowel disease aims to induce and maintain disease remission, avoid complica-tions, and restore quality of life. The treatments include the ...
Overexpression of Glutamate Decarboxylase in Mesenchymal Stem Cells Enhances Their Immunosuppressive Properties and Increases GABA and Nitric Oxide Levels
(2016)
The neurotransmitter GABA has been recently identified as a potent immunosuppressive agent that targets both innate and adaptive immune systems and prevents disease progression of several autoimmunity models. Mesenchymal ...
Pulpal lesions in normal and cyclosporin a treated rats
(1997-12-01)
The objective of this study was to examine the development of pulpal lesions in the lower molar of control and cyclosporin A (CyA) treated rats. The pulps of the first lower molars of 20 normal and 20 CyA treated rats were ...
Morphometric evaluation of gingival overgrowth and regression caused by cyclosporin in rats
(2001-12-01)
Cyclosporin A is a selective immunosuppressant, used in organ transplants to prevent graft rejection. Cyclosporin A can cause various side effects including gingival overgrowth. The aim of this work was to evaluate gingival ...
Morphometric evaluation of gingival overgrowth and regression caused by cyclosporin in rats
(2001-12-01)
Cyclosporin A is a selective immunosuppressant, used in organ transplants to prevent graft rejection. Cyclosporin A can cause various side effects including gingival overgrowth. The aim of this work was to evaluate gingival ...