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Phosphodiesterase inhibitor pentoxifylline: An antiinflammatory/immunomodulatory drug potentially useful in some rheumatic diseases
Phosphodiesterase inhibitor pentoxifylline: an antiinflammatory/immunomodulatory drug potentially useful in some rheumatic diseases: Adjuvants, Immunologic/therapeutic use, Animals, Anti-Inflammatory Agents, Non-Steroida ...
Progress in nano-drug delivery of artemisinin and its derivatives: towards to use in immunomodulatory approaches
(Taylor & Francis Ltd, 2018-01-01)
In recent years, artemisinin (ART) and its derivatives have highlighted according to their effects on highly aggressive cancers, as well as treatment of malaria and leishmaniasis, besides presenting anti-inflammatory and ...
Should mast cells be considered therapeutic targets in multiple sclerosis?
(2020-11-01)
Mast cells are immune cells of the myeloid lineage that are found throughout the body, including the central nervous system. They perform many functions associated with innate and specific immunity, angiogenesis, and ...
Immunomodulatory-based therapy as a potential promising treatment strat- egy against severe covid-19 patients: A systematic review
The global panic of the novel coronavirus disease 2019 (COVID-19) triggered by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to an urgent requirement for effective
therapy. COVID-19 infection, ...
Immunomodulatory activity of an anti-HSV-1 synthetic stigmastane analog
(Elsevier, 2012-11)
Many viral infections are associated with the development of immunopathologies and autoimmune diseases, which are of difficult treatment and for which no vaccines are yet available. Obtaining compounds that conjugate both ...
Propolis antiviral and immunomodulatory activity: A review and perspectives for COVID-19 treatment
(2021-01-01)
Objectives Viral outbreaks are a frequent concern for humans. A great variety of drugs has been used to treat viral diseases, which are not always safe and effective and may induce adverse effects, indicating the need for ...
Natural and semisynthetic diterpenoids with antiviral and immunomodulatory activities block the ERK signaling pathway
(Springer, 2015-10)
The pathogenesis of many viral infections lies on the damage caused by the immune response against the virus. Current antiviral drugs do not act on the inflammatory component of the disease. Thus, new compounds that inhibit ...
Protein-glycan interactions in immunoregulation: galectins as tuners of the inflammatory response
(Scion Publishing Ltd, 2007)
Protein-glycan interactions mediate a variety of biological processes including cell trafficking, activation, differentiation, and survival. Galectins, a growing family of animal lectins defined by shared consensus amino ...