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Genome-level determination of Plasmodium falciparum blood-stage targets of malarial clinical immunity in the Peruvian Amazon
(Oxford University Press, 2015)
BACKGROUND: Persons with blood-stage Plasmodium falciparum parasitemia in the absence of symptoms are considered to be clinically immune. We hypothesized that asymptomatic subjects with P. falciparum parasitemia would ...
CLINICAL IMMUNOLOGY AS A NEW SPECIALTY IN PUBLIC HEALTH: A MODEL FOR DEVELOPING COUNTRIES
(Bulletin of the Pan American Health Organization, 2016)
Automatic Generation of Validated Specific Epitope Sets
(Hindawi, 2015)
Accurate measurement of B and T cell responses is a valuable tool to study autoimmunity, allergies, immunity to pathogens, and host-pathogen interactions and assist in the design and evaluation of T cell vaccines and ...
Anti-Taenia solium monoclonal antibodies for the detection of parasite antigens in body fluids from patients with neurocysticercosis
(Elsevier, 2016)
Neurocysticercosis (NCC), an infection of the brain by Taenia solium (Ts) cysts, is the most common cause of adult-onset epilepsy in developing countries. Serological testing consists primarily of varying methods to detect ...
Development and validation of a broad scheme for prediction of HLA class II restricted T cell epitopes
(Elsevier, 2015)
Computational prediction of HLA class II restricted T cell epitopes has great significance in many immunological studies including vaccine discovery. In recent years, prediction of HLA class II binding has improved ...
Immune response to glutaraldehyde-treated cells. I. Dissociation of immunological memory and antibody production
(1979)
Glutaraldehyde (GA)-treated sheep red blood cells (SRBC) or H-2 allogeneic spleen cells (SC), induced immunological memory with absent or markedly reduced primary antibody production. In contrast, a normal secondary response ...
Laboratory Evaluation of a Dual-Path Platform Assay for Rapid Point-of-Care HIV and Syphilis Testing
(American Society for Microbiology, 2016)
We assessed the laboratory performance of the Chembio dual-path platform HIV-syphilis rapid immunodiagnostic test and electronic reader for detection of HIV and Treponema pallidum antibodies in 450 previously characterized ...
Post-treatment vascular leakage and inflammatory responses around brain cysts in porcine neurocysticercosis
(Public Library of Science, 2015)
Cysticidal treatment of neurocysticercosis, an infection of humans and pig brains with Taenia solium, results in an early inflammatory response directed to cysts causing seizures and focal neurological manifestations. ...
A Comparative Study of Peripheral Immune Responses to Taenia solium in Individuals with Parenchymal and Subarachnoid Neurocysticercosis
(Public Library of Science, 2015)
BACKGROUND: The ability of Taenia solium to modulate the immune system likely contributes to their longevity in the human host. We tested the hypothesis that the nature of the immune response is related to the location of ...