Células tronco pluripotentes são uma ferramenta fundamental para os estudos da embriologia, para o desenvolvimento de estudos clínicos in vitro, para a medicina regenerativa e mais recentemente, para a produção de gametas ...

Mitochondrial dysfunctions caused by mutations in the mitochondrial DNA (mtDNA) represent an important group of human pathologies. However, it is not possible to predict with accuracy the risk of a woman with mutant mtDNA ...

The event of cellular reprogramming into pluripotency is influenced by several factors, such as in vitro culture conditions (e.g., culture medium and oxygen concentration). Herein, bovine iPSCs (biPSCs) were generated in ...

Stem cells are undifferentiated and self-renewable cells that present new possibilities for both regenerative medicine and the understanding of early mammalian development. Adult multipotent stem cells are already widely ...

The generation of renal organoids can be a powerful tool for investigate genetic diseases such as autosomal polycystic kidney disease dominant (DRPAD). This methodology basically employs cells adult somatics that are ...

The cellular reprogramming into pluripotency is influenced by external and internal cellular factors, such as in vitro culture conditions (e.g., environmental oxygen concentration), and the aging process. Herein, we aimed ...

Cockayne syndrome (CS) is a human premature aging disorder associated with neurological and developmental abnormalities, caused by mutations mainly in the CS group B gene (ERCC6). At the molecular level, CS is characterized ...

Perovskite solar cells with carbon electrodes (C-PSCs) are one of the low-cost and new-generation solar cell technologies to solve global energy demands. In the current research, an additive engineering approach to a ...