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Dengue induces iNOS expression and nitric oxide synthesis in platelets through IL-1R
(Frontiers Media, 2023)
Inhibition of iNOS induces antidepressant-like effects in mice: Pharmacological and genetic evidence
(PERGAMON-ELSEVIER SCIENCE LTDOXFORD, 2012)
Recent evidence has suggested that systemic administration of non-selective NOS inhibitors induces antidepressant-like effects in animal models. However, the precise involvement of the different NOS isoforms (neuronal-nNOS ...
Effects of rotenone and pyridaben on complex I electron transfer and on mitochondrial nitric oxide synthase functional activity
(Springer Verlag Berlín, 2010-10)
Rotenone and pyridaben were tested on activities and properties of rat brain mitochondria determining Ki (inhibitor concentration at half maximal inhibition) and Imax (% of inhibition at maximal inhibitor concentration). ...
iNOS-Derived Nitric Oxide Stimulates Osteoclast Activity and Alveolar Bone Loss in Ligature-Induced Periodontitis in Rats
(Amer Acad Periodontology, 2011-11-01)
Background: Inflammatory stimuli activate inducible nitric oxide synthase (iNOS) in a variety of cell types, including osteoclasts (OC) and osteoblasts, resulting in sustained NO production. In this study, we evaluate the ...
iNOS-Derived Nitric Oxide Stimulates Osteoclast Activity and Alveolar Bone Loss in Ligature-Induced Periodontitis in Rats
(Amer Acad Periodontology, 2011-11-01)
Background: Inflammatory stimuli activate inducible nitric oxide synthase (iNOS) in a variety of cell types, including osteoclasts (OC) and osteoblasts, resulting in sustained NO production. In this study, we evaluate the ...
Relevance of iNOS expression in tumor growth and maintenance of cancer stem cells in a bladder cancer model
(Springer, 2020-11)
The expression of inducible nitric oxide (NO) synthase (iNOS) in human bladder cancer (BC) is a poor prognostic factor associated with invasion and tumor recurrence. Here, we evaluated the relevance of iNOS expression in ...
Immunohistochemical approach reveals involvement of inducible nitric oxide synthase in rat late development
(SPRINGER, 2009)
To better understand the role of nitric oxide (NO) in mammal development, specifically in the transition of the fetal stages at birth, we studied the timing of cell-specific expression of inducible NO synthase (iNOS) isoform ...