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Pharmacokinetics of hydroxymethylnitrofurazone and its parent drug nitrofurazone in rabbits

Nogueira Filho, Marco Antonio Ferraz; Padilha, Elias Carvalho; Campos, Michel Leandro de; Machado, Diego Vinicius de Pontes; Davanço, Marcelo Gomes; Pestana, Kelly Christina; Chin, Chung Man; Peccinini, Rosângela Gonçalves (Drug Metabolism Letters, 2015)

Pharmacokinetics of hydroxymethylnitrofurazone and its parent drug nitrofurazone in rabbits

Universidade Estadual Paulista (UNESP) (2013-01-01)

The prodrug hydroximethylnitrofurazone (NFOH) presents antichagasic activity with greatly reduced toxicity compared to its drug matrix nitrofurazone (NF). Besides these new characteristics, the prodrug was more active ...

Pharmacokinetics of hydroxymethylnitrofurazone and its parent drug nitrofurazone in rabbits

Universidade Estadual Paulista (Unesp) (Drug Metabolism Letters, 2013)

The prodrug hydroximethylnitrofurazone (NFOH) presents antichagasic activity with greatly reduced toxicity compared to its drug matrix nitrofurazone (NF). Besides these new characteristics, the prodrug was more active ...

Pharmacokinetics of hydroxymethylnitrofurazone and its parent drug nitrofurazone in rabbits

Nogueira Filho, Marco Antonio Ferraz; Padilha, Elias Carvalho; Campos, Michel Leandro de; Machado, Diego Vinicius de Pontes; Davanço, Marcelo Gomes; Pestana, Kelly Christina; Chin, Chung Man; Peccinini, Rosângela Gonçalves [UNESP] (Drug Metabolism Letters, 2015)