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Alpha-melanocyte-stimulating hormone through melanocortin-4 receptor inhibits nitric oxide synthase and cyclooxygenase expression in the hypothalamus of male rats
(Karger, 2004-12)
There is evidence that α-melanocyte-stimulating hormone (α-MSH) has immunomodulatory and anti-inflammatory actions within the brain. In this study, we tested whether these actions are due to inhibition of the synthesis of ...
Respiratory medication used in COPD patients from seven Latin American countries : The lassyc study
(2018)
Background: Limited information is available regarding medication use in COPD patients from Latin America. This study evaluated the type of medication used and the adherence to different inhaled treatments in stable COPD ...
Progestin and antiprogestin responsiveness in breast cancer is driven by the PRA/PRB ratio via AIB1 or SMRT recruitment to the CCND1 and MYC promoters
(John Wiley & Sons Inc, 2014-11-12)
There is emerging interest in understanding the role of progesterone receptors (PRs) in breast cancer. The aim of this study was to investigate the proliferative effect of progestins and antiprogestins depending on the ...
Análise morfológica, imuno-histoquímica e ultraestrutural dos efeitos da exposição ao flavonóide crisina sobre a próstata de gerbilos adultos
(Universidade Estadual Paulista (Unesp), 2018-02-23)
A crisina é um composto natural biologicamente ativo encontrado predominantemente em flores de maracujá azul, em mel, camomila, própolis e casca de frutas. Possui propriedades potentes como efeito anti-inflamatório, ...
Ghrelin as a neuroprotective and palliative agent in Alzheimer's and Parkinson's disease
(Bentham Science Publishers, 2013-07)
Ghrelin is a gastric hormone that stimulates growth hormone (GH) secretion and food intake to regulate energy homeostasis and body weight by binding to its receptor, GH secretagogue receptor (GHSR1a), which is most highly ...
Ethopharmacological evaluation of the rat exposure test: A prey-predator interaction test
(2013-03-01)
The rat exposure test (RET) is a prey (mouse)-predator (rat) situation that activates brain defensive areas and elicits hormonal and defensive behavior in the mouse. Here, we investigated possible correlations between the ...