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Chronic hepatitis C: Hepatic fibrosis evolution after ineffective specific treatment
(H G E UPDATE MEDICAL PUBLISHING S A, 2008)
Background/Aims: Specific treatment of chronic hepatitis C is effective in 50% of patients, improving the]liver`s fibrosis, necroinflammatory changes and steatosis. However, in patients still viremic after treatment the ...
The association of cryoglobulinaemia with sustained virological response in patients with chronic hepatitis C
(Wiley-blackwellMaldenEUA, 2011)
Association of genetic polymorphisms with histological grading of necroinflammation, staging of fibrosis, and liver function in mexicans with chronic hepatitis c virus infection
(2013)
Background/Aim: The aim of this work was to establish an association between the single-nucleotide polymorphisms (SNPs) of TGFB1 (rs1800471), AT (rs3789679),MMP-1 (rs17886084), MMP-3 (rs35068180), and PAI-1 (rs1799889) and ...
Association of genetic polymorphisms with histological grading of necroinflammation, staging of fibrosis, and liver function in mexicans with chronic hepatitis c virus infection
(2013)
Background/Aim: The aim of this work was to establish an association between the single-nucleotide polymorphisms (SNPs) of TGFB1 (rs1800471), AT (rs3789679),MMP-1 (rs17886084), MMP-3 (rs35068180), and PAI-1 (rs1799889) and ...
Histological response study of chronic viral hepatitis C patients treated with interferon alone or combined with ribavirin
(Brazilian Society of Infectious Diseases, 2008)
Chronic hepatitis C is often a progressive, fibrotic disease that can lead to cirrhosis and other complications. The recommended therapy is a combination of interferon and ribavirin. Besides its antiviral action, interferon ...
Serum levels of Th17 associated cytokines in chronic hepatitis C virus infection
(2012)
The Th17-mediated immune response was investigated in patients chronically infected with hepatitis C virus (HCV) by determining the serum levels of the cytokines involved in the induction of the Th17 response (TGF-β and ...
Noninvasive biomarkers in NAFLD and NASH — current progress and future promise
(Nature Publishing Group, 2018-08)
Nonalcoholic fatty liver disease (NAFLD) affects 25% of the global adult population and is the most common chronic liver disease worldwide. Nonalcoholic steatohepatitis (NASH) is the active form of NAFLD, with hepatic ...
Treatment with pirfenidone for two years decreases fibrosis, cytokine levels and enhances CB2 gene expression in patients with chronic hepatitis C
(2014)
Background: The aim of this study was to assess whether two-years treatment with Pirfenidone influences necroinflammation, fibrosis and steatosis, serum levels of TGF-β1, IL-6, TNF-α and CB1 and CB2 gene expression, in ...
Treatment with pirfenidone for two years decreases fibrosis, cytokine levels and enhances CB2 gene expression in patients with chronic hepatitis C
(2014)
Background: The aim of this study was to assess whether two-years treatment with Pirfenidone influences necroinflammation, fibrosis and steatosis, serum levels of TGF-?1, IL-6, TNF-? and CB1 and CB2 gene expression, in ...