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Endoplasmic reticulum-localized hepatic lipase decreases triacylglycerol storage and VLDL secretion
(Elsevier, 2013-06)
Hepatic triacylglycerol levels are governed through synthesis, degradation and export of this lipid. Here we demonstrate that enforced expression of hepatic lipase in the endoplasmic reticulum in McArdle RH7777 hepatocytes ...
On the mechanism of protective action of cold acclimatization against carbon tetrachloride - and ethionine-induced fatty liver
(Fundação Oswaldo Cruz. Instituto Oswaldo Cruz., 2020)
High density lipoprotein is an inappropiate substrate for hepatic lipase in postmenopausal women
(Elsevier Science, 2012-09)
Background HDL antiatherogenic effects would not only depend on its concentration but also on its biological quality. Hepatic lipase (HL) action on HDL acts in one of the last steps of reverse cholesterol transport. ...
Effects of anabolic androgenic steroids on chylomicron metabolism
(ELSEVIER SCIENCE INCNEW YORK, 2013-08-02)
Objective: To evaluate the effects of anabolic androgenic steroids (AAS) on chylomicron metabolism. Methods: An artificial lipid emulsion labeled with radioactive cholesteryl ester (CE) and triglycerides (TG) mimicking ...
Pharmacological intervention of liver triacylglycerol lipolysis: The good, the bad and the ugly
(Pergamon-Elsevier Science Ltd, 2018-09)
Excessive triacylglycerol (TG) accumulation is the distinctive feature of obesity. In the liver, sustained TG accretion leads to nonalcoholic fatty liver disease (NAFLD), eventually progressing to non-alcoholic steatohepatitis ...
Role of SN1 lipases on plasma lipids in metabolic syndrome and obesity
(American Heart Association, 2014-03)
Objective—To assess the phospholipase activity of endothelial (EL) and hepatic lipase (HL) in postheparin plasma of subjects with metabolic syndrome (MS)/obesity and their relationship with atherogenic and antiatherogenic ...
Post-menopausal hormone therapy reduces autoantibodies to oxidized apolipoprotein B100
(INFORMA HEALTHCAREEstados Unidos, 2011)