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Characterization of protein synthesis initiation factor 2 from Xenopus laevis oocytes
(1988)
The protein synthesis initiation factor 2 (eIF2) from Xenopus laevis oocytes has been extensively purified and characterized. Depending upon the purification scheme, eIF2 containing three subunits (α, β and γ) with Mr of ...
Molecular basis of ligand dissociation in β-adrenergic receptors
(Public Library of Science, 2011)
The important and diverse biological functions of β-adrenergic receptors (βARs) have promoted the search for compounds to stimulate or inhibit their activity. In this regard, unraveling the molecular basis of ligand ...
Interaction of protein synthesis initiation factor 2 from Xenopus laevis oocytes with GDP and GTP analogs
(1987)
The structural specificity of the purified protein synthesis initiation factor 2 (eIF-2) from X. laevis ovary towards analogs of GTP and GDP was studied. The relative affinity of the structural analogs was measured by their ...
Positive selection results in frequent reversible amino acid replacements in the G protein gene of human respiratory syncytial virus
(2009-01-01)
Human respiratory syncytial virus (HRSV) is the major cause of lower respiratory tract infections in children under 5 years of age and the elderly, causing annual disease outbreaks during the fall and winter. Multiple ...
Positive selection results in frequent reversible amino acid replacements in the G protein gene of human respiratory syncytial virus
(2009-01-01)
Human respiratory syncytial virus (HRSV) is the major cause of lower respiratory tract infections in children under 5 years of age and the elderly, causing annual disease outbreaks during the fall and winter. Multiple ...
A GWAS in Latin Americans highlights the convergent evolution of lighter skin pigmentation in Eurasia
(Springer Nature, 2019)
We report a genome-wide association scan in >6,000 Latin Americans for pigmentation of skin and eyes. We found eighteen signals of association at twelve genomic regions. These include one novel locus for skin pigmentation ...