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Non-canonical roles of tRNAs and tRNA mimics in bacterial cell biology
(Wiley-Blackwell, 2016)
Transfer RNAs (tRNAs) are the macromolecules that transfer activated amino acids from aminoacyl-tRNA synthetases to the ribosome, where they are used for the mRNA guided synthesis of proteins. Transfer RNAs are ancient ...
A tRNA(Glu) that uncouples protein and tetrapyrrole biosynthesis
(ELSEVIER SCIENCE, 2005-11-21)
Glu-tRNA is either bound to elongation factor Tu to enter protein synthesis or is reduced by glutamyl-tRNA reductase (GluTR) in the first step of tetrapyrrole biosynthesis in most bacteria, archaea and in chloroplasts. ...
Coevolution of an aminoacyl-tRNA synthetase with its tRNA substrates
(NATL ACAD SCIENCES, 2003-11-25)
Glutamyl-tRNA synthetases (GluRSs) occur in two types, the discriminating and the nondiscriminating enzymes. They differ in their choice of substrates and use either tRNA(Glu) or both tRNA(Glu) and tRNA(Gln). Although most ...
TRANSFER-RNA DEPENDENT AMIDOTRANSFERASES KEY ENZYMES FOR ASN-TRNA AND GLU-TRNA SYNTHESIS IN NATURE
(LANDES BIOSCIENCE, 2004)
Transfer RNA-dependent amidotransferases (AdTs) are essential for Gln-tRNA Gln and Asn-tRNA Asn synthesis in organisms lacking glutaminyl-or asparaginyl-tRNA synthetase. In the presence of ATP and an amide donor, AdT ...