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Impact of heterologous expression of Escherichia coli UDP-glucose pyrophosphorylase on trehalose and glycogen synthesis in Corynebacterium glutamicum
(AMER SOC MICROBIOLOGY, 2004)
Trehalose is a disaccharide with a wide range of applications in the food industry. We recently proposed a strategy for trehalose production based on improved strains of the gram-positive bacterium Corynebacterium glutamicum. ...
Resolution of the direct interaction with and inhibition of the human glut1 hexose transporter by resveratrol from its effect on glucose accumulation
(AMERICAN PHYSIOLOGICAL SOCIETY, 2013)
The production and utilization of GDP-glucose in the biosynthesis of trehalose-6-phosphate by Streptomyces venezuelae
(American Society for Biochemistry and Molecular Biology, 2017-01)
Trehalose-6-phosphate synthase OtsA from streptomycetes is unusual in that it uses GDP-glucose as the donor substrate rather than the more commonly used UDP-glucose. We now confirm that OtsA from Streptomyces venezuelae ...
LRP1-Mediated AggLDL endocytosis promotes pholesteryl ester accumulation and impairs insulin response in HL-1 cells
(MDPI, 2020-01)
The cardiovascular disease (CVD) frequently developed during metabolic syndrome and type-2 diabetes mellitus is associated with increased levels of aggregation-prone small LDL particles. Aggregated LDL (aggLDL) internalization ...
A Chimeric UDP-Glucose Pyrophosphorylase Produced by Protein Engineering Exhibits Sensitivity to Allosteric Regulators
(Molecular Diversity Preservation International, 2013-05)
In bacteria, glycogen or oligosaccharide accumulation involves glucose-1-phosphate partitioning into either ADP-glucose (ADP-Glc) or UDP-Glc. Their respective synthesis is catalyzed by allosterically regulated ADP-Glc ...