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Pharmacogenomics of Hypertension and Preeclampsia: Focus on Gene-Gene Interactions
(Frontiers Media Sa, 2018-02-28)
Hypertension is a leading cause of cardiovascular mortality, but only about half of patients on antihypertensive therapy achieve blood pressure control. Preeclampsia is defined as pregnancy-induced hypertension and ...
Gene-gene and gene-environment interactions as modifier factors of prostatic cancer risk: (a case-only) design study
(SOCIEDAD MEDICA DE SANTIAGO, 2004)
Genes that code for T cell signaling proteins establish transcriptional regulatory networks during thymus ontogeny
(SPRINGER, 2008)
Gene expression profiling by cDNA microarrays during murine thymus ontogeny has contributed to dissecting the large-scale molecular genetics of T cell maturation. Gene profiling, although useful for characterizing the ...
Polycation-Based Gene Therapy: Current Knowledge and New Perspectives
(Bentham Science Publ Ltd, 2011-08-01)
At present, gene transfection insufficient efficiency is a major drawback of non-viral gene therapy. The 2 main types of delivery systems deployed in gene therapy are based on viral or non-viral gene carriers. Several ...
The relation between hairpin formation by mitochondrial WANCY tRNAs and the occurrence of the light strand replication origin in Lepidosauria
(Elsevier, 2014)
Mitochondrial light strand DNA replication is initiated at light strand replication origins (OLs), short stem-loop hairpins formed by the heavy strand DNA. OL-like secondary structures are also formed by heavy strand DNA ...