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Mining Gene Regulatory Networks by Neural Modeling of Expression Time-Series
(IEEE Computer Society, 2015-11)
Discovering gene regulatory networks from data is one of the most studied topics in recent years. Neural networks can be successfully used to infer an underlying gene network by modeling expression profiles as times series. ...
Modelagem computacional de redes genéticas regulatórias
(Universidade Federal de Santa MariaBRFísicaUFSMPrograma de Pós-Graduação em Física, 2016-09-30)
In biology, regulatory networks are sets of macromolecules, mostly proteins and
RNAs that interact to execute task. The main players in regulatory networks are DNAbinding
proteins, also called transcription factors as they ...
Gene regulatory network inference and analysis of multidrug-resistant Pseudomonas aeruginosa
(Fundação Oswaldo Cruz, 2019)
On Artificial Gene Regulatory Networks
(Sociedad Argentina de Informática E Investigación Operativa, 2008-12)
Gene regulatory networks (GRNs) represent dependencies between genes and their products during protein synthesis at the molecular level. At the present there exist many inference methods that infer GRNs form observed data. ...
A framework to shift basins of attraction of gene regulatory networks through batch reinforcement learning
(2020-05-16)
A major challenge in gene regulatory networks (GRN) of biological systems is to discover when and what in-terventions should be applied to shift them to healthy phenotypes. A set of gene activity profiles, called basin ...
Reverse engineering directed gene regulatory networks from transcriptomics and proteomics data of biomining bacterial communities with approximate Bayesian computation and steady-state signalling simulations
(2020)
Abstract
Background
Network inference is an important aim of systems biology. It enables the transformation of OMICs datasets into biological knowledge. It consists of ...
Exploring in silico transcriptional and post-transcriptional gene regulatory networks in the Corynebacterium genus
(Universidade Federal de Minas GeraisBrasilICB - DEPARTAMENTO DE BIOLOGIA GERALPrograma de Pós-Graduação em BioinformaticaUFMG, 2021-05-27)
Transcriptional and post-transcriptional regulation of gene expression are considered key regulatory steps in bacteria. Regulatory molecules such as transcription factors (TF), sigma-factors and small RNAs (sRNAs) modulate ...