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Pharmacogenomics of Hypertension and Preeclampsia: Focus on Gene-Gene Interactions
(Frontiers Media Sa, 2018-02-28)
Hypertension is a leading cause of cardiovascular mortality, but only about half of patients on antihypertensive therapy achieve blood pressure control. Preeclampsia is defined as pregnancy-induced hypertension and ...
Gene-gene and gene-environment interactions as modifier factors of prostatic cancer risk: (a case-only) design study
(SOCIEDAD MEDICA DE SANTIAGO, 2004)
Gene-gene interaction for nonsyndromic cleft lip with or without cleft palate in chilean case-parent trios
(Elsevier, 2018-07)
Objective: Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is a birth defect for which several genes susceptibility genes been proposed. Consequently, it has been suggested that many of these genes belong to ...
Integrative meta-analysis identifies microRNA-regulated networks in infantile hemangioma
(2016-01-15)
Background: Hemangioma is a common benign tumor in the childhood; however our knowledge about the molecular mechanisms of hemangioma development and progression are still limited. Currently, microRNAs (miRNAs) have been ...
Interactions of polymorphisms in different clock genes associated with circadian phenotypes in humans
(Sociedade Brasileira de Genética, 2010-01-01)
Several studies have shown that mutations and polymorphisms in clock genes are associated with abnormal circadian parameters in humans and also with more subtle non-pathological phenotypes like chronotypes. However, there ...
Interactions of polymorphisms in different clock genes associated with circadian phenotypes in humans
(Sociedade Brasileira de Genética, 2010)
Several studies have shown that mutations and polymorphisms in clock genes are associated with abnormal circadian parameters in humans and also with more subtle non-pathological phenotypes like chronotypes. However, there ...