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Investigation of Thrombin Activity with PAR 1-based Fluorogenic Peptides
(Bentham Science Publ Ltd, 2013-10-01)
Thrombin, a highly specific protease of blood coagulation, has two exosites that modulate its specificity. We designed two sets of synthetic substrate FRET peptides with 25- or 11-amino acids (aa) each, based on the PAR 1 ...
ZapA, a possible virulence factor from Proteus mirabilis exhibits broad protease substrate specificity
(Associação Brasileira de Divulgação Científica (ABRADIC), 2001-11-01)
The opportunistic bacterium Proteus mirabilis secretes a metalloprotease, ZapA, considered to be one of its virulence factors due to its IgA-degrading activity. However, the substrate specificity of this enzyme has not yet ...
ZapA, a possible virulence factor from Proteus mirabilis exhibits broad protease substrate specificity
(Associação Brasileira de Divulgação Científica (ABRADIC), 2001-11-01)
The opportunistic bacterium Proteus mirabilis secretes a metalloprotease, ZapA, considered to be one of its virulence factors due to its IgA-degrading activity. However, the substrate specificity of this enzyme has not yet ...
ZapA, a possible virulence factor from Proteus mirabilis exhibits broad protease substrate specificity
(Associação Brasileira de Divulgação Científica (ABRADIC), 2014)
Characterization of a kinin inactivating serine endopeptidase H2 (kininase) from human urine using fluorogenic substrates
(Elsevier B.V., 1999-12-01)
We have previously described a kinin-inactivating endopeptidase (H2), which was purified 19-fold from human urine by DEAE-cellulose chromatography and gel filtration. the enzyme was inhibited 100% by PMSF, TPCK and pOHMB. ...
Expression and substrate specificity of a recombinant cysteine proteinase B of Leishmania braziliensis
(Elsevier B.V., 2008-10-01)
The cysteine proteinase B of Leishmania parasites is an important virulence factor. in this study we have expressed, isolated and characterized for the first time a recombinant CPB from Leishmania braziliensis, the causative ...
Intramolecularly quenched fluorogenic peptide substrates for human renin
(Academic Press Inc Jnl-comp Subscriptions, 1992-05-15)
Specific fluorogenic substrates for neprilysin (neutral endopeptidase, EC 3.4.24.11) which are highly resistant to serine- and metalloproteases
(Associação Brasileira de Divulgação Científica, 1997-10-01)
Two intramolecularly quenched fluorogenic peptides containing o-aminobenzoyl (Abz) and ethylenediamine 2,4-dinitrophenyl (EDDnp) groups at amino- and carboxyl-terminal amino acid residues, Abz-<!-- $MVD$:face(Times) ...
Evaluation of the catalytic specificity, biochemical properties, and milk clotting abilities of an aspartic peptidase from Rhizomucor miehei
(Springer, 2016-08-01)
In this study, we detail the specificity of an aspartic peptidase from Rhizomucor miehei and evaluate the effects of this peptidase on clotting milk using the peptide sequence of k-casein (Abz-LSFMAIQ-EDDnp) and milk powder. ...
The Identification and Biochemical Properties of the Catalytic Specificity of a Serine Peptidase Secreted by Aspergillus fumigatus Fresenius
(Bentham Science Publ Ltd, 2014-01-01)
Aspergillus fumigatus is a saprophytic fungus as well as a so-called opportunist pathogen. Its biochemical potential and enzyme production justify intensive studies about biomolecules secreted by this microorganism. We ...