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Comportamento fenotípico e perfil de suscetibilidade de C. dubliniensis resistentes ao fluconazol frente a antifúngicos e associações
(Universidade Federal de Santa MariaBRFarmáciaUFSMPrograma de Pós-Graduação em Ciências Farmacêuticas, 2009-11-23)
Widespread and prolonged usage of azoles in recent years has led to the rapid
development of drug resistance in Candida species. In Candida albicans, resistance to
fluconazole causes cross-resistance to other antifungals ...
Atividade das equinocandinas, anfotericina B e voriconazol frente a isolados de Candida glabrata sensíveis e resistentes ao fluconazol
(Universidade Federal de Santa MariaBRFarmáciaUFSMPrograma de Pós-Graduação em Ciências Farmacêuticas, 2012-02-28)
Widespread and prolonged usage of azoles in recent years has led to the rapid
development of drug resistance in Candida species. In Candida albicans, resistance to
fluconazole causes cross-resistance to other antifungals ...
Avaliação da suscetibilidade de Candida glabrata resistentes ao fluconazol frente a combinações de antifúngicos
(Universidade Federal de Santa MariaBRFarmáciaUFSMPrograma de Pós-Graduação em Ciências Farmacêuticas, 2011-03-25)
In the last decades the invasive mycoses caused by opportunistic fungi has showed a significant growth. The extensive use of azoles showed that the development of resistance of Candida species to these drugs is an emergent ...
Fluconazole impacts the extracellular matrix of fluconazole-susceptible and -resistant Candida albicans and Candida glabrata biofilms
(2018-01-01)
Background: Fluconazole (FLZ) is a drug commonly used for the treatment of Candida infections. However, β-glucans in the extracellular matrices (ECMs) hinder FLZ penetration into Candida biofilms, while extracellular DNA ...
Effect of Potassium on Saccharomyces cerevisiae Resistance to Fluconazole
(American Society for Microbiology, 2001-05)
Susceptibility of strain S288c of Saccharomyces cerevisiae to fluconazole was assayed in the presence and absence of KCl. Addition of 150 mM KCl renders the strain more sensitive to the antifungal agent. The effect is ...
Impact of resistance to fluconazole on virulence and morphological aspects of Cryptococcus neoformans and Cryptococcus gattii isolates
(2016-02-16)
Cryptococcus sp. are responsible for around 1 million cases of meningitis every year. Fluconazole (FLU) is commonly used in the treatment of cryptococcosis, mainly in immunocompromised patients and the resistance is usually ...
Fluconazole and itraconazole resistance of yeasts isolated from the bloodstream and catheters of hospitalized pediatric patients
(2006)
Background: In critically ill children, Candida species and other yeasts appear as an important nosocomial pathogen. The emerging fungal pathogens are usually less susceptible to azole compounds, and the management of such ...
Fungicidal effect of photodynamic therapy against fluconazole-resistant Candida albicans and Candida glabrata
(Wiley-Blackwell, 2011-03-01)
Although photodynamic therapy (PDT) has shown great promise for the inactivation of Candida species, its effectiveness against azole-resistant pathogens remains poorly documented. This in vitro study describes the association ...