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The 'brain shadowing sign': a novel marker of fetal craniosynostosis
(Bmj Publishing Group, 2016)
Introduction: The prenatal diagnosis of fetal craniosynostosis is challenging, especially in single-suture cases. When sutures are obliterated, sound waves fail to penetrate the cortical bone, creating an evident acoustic ...
Transcriptomics of the late gestation ovine fetal brain: modeling the co-expression of immune marker genes
(BioMed Central, 2014-11)
Background: Major changes in gene expression occur in the fetal brain to modulate the function of this organ postnatally. Thus, factors can alter the genomics of the fetal brain, predisposing to neurological disorders later ...
Uterine artery blood flow, fetal hypoxia and fetal growth
(Philosophycal Transactions B, 2015-03-13)
Evolutionary trade-offs required for bipedalism and brain expansion influence
the pregnancy rise in uterine artery (UtA) blood flow and, in turn, reproductive
success. We consider the importance of UtA blood flow by ...
Gestational hypoxia and blood-brain barrier permeability: early origins of cerebrovascular dysfunction induced by epigenetic mechanisms
(Frontiers Media, 2021)
Fetal chronic hypoxia leads to intrauterine growth restriction (IUGR), which is likely to
reduce oxygen delivery to the brain and induce long-term neurological impairments.
These indicate a modulatory role for oxygen in ...
Ketamine reduces inflammation pathways in the hypothalamus and hippocampus following transient hypoxia in the late-gestation fetal sheep
(Frontiers Media S.A., 2019-01-07)
The physiological response to hypoxia in the fetus has been extensively studied with regard to redistribution of fetal combined ventricular output and sparing of oxygen delivery to fetal brain and heart. Previously, we ...
Fetal Central Nervous System and Thymic Alterations Following Cyclophosphamide Treatment of Pregnant Mice
(Sociedad Chilena de Anatomía, 2007)
Induction of ABCG2/BCRP restricts the distribution of zidovudine to the fetal brain in rats
(Academic Press Inc Elsevier Science, 2017-09)
Safety concerns for fetus development of zidovudine (AZT) administration as prophylaxis of vertical transmission of HIV persist. We evaluated the participation of the ATP-binding cassette efflux transporter ABCG2 in the ...
Cellular Oxidative/Antioxidant Balance in γ-Irradiated Brain: An Update
(Bentham Science Publishers, 2016-07)
Both epidemiological and experimental data indicate that ionizing radiation (IR) may disrupt developmental processes leading to deleterious effects on brain functions. A central role of reactive oxygen (ROS) and nitrogen ...