Cephalosporin C, a b -lactam antibiotic, is the starting molecule for industrial production of semi-synthetic cephalosporins. The bioprocess for its production is carried out in batch stirred and aerated tank reactors ...

Cephalosporin C, a b -lactam antibiotic, is the starting molecule for industrial production of semi-synthetic cephalosporins. The bioprocess for its production is carried out in batch stirred and aerated tank reactors ...

The objective of this work was to study the operational feasibility of nitrification and denitrification processes in a mechanically stirred sequencing batch reactor (SBR) operated in batch and fed-batch mode. The reactor ...

This paper deals with the design of feeding rates for dual-substrate fed-batch processes where the main control objective is the regulation of the microbial growth rate. To this end, feedback of the growth rate error is ...

Immobilized cell utilization in tower-type bioreactor is one of the main alternatives being studied to improve the industrial bioprocess. Other alternatives for the production of beta -lactam antibiotics, such as a ...

Immobilized cell utilization in tower-type bioreactor is one of the main alternatives being studied to improve the industrial bioprocess. Other alternatives for the production of beta -lactam antibiotics, such as a ...

A novel extremum seeking scheme is proposed for the optimization of the specific growth rate in fed-batch processes with substrate inhibited kinetics. The proposed controller is based on a high order sliding mode algorithm, ...

A mathematical optimal control strategy for feeding operation was developed for fed-batch enzymatic hydrolysis of dilute acid pretreated lignocellulosic biomass based on a modified epidemic model. Cellulose conversion was ...