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Control of liver glucokinase activity: a potential new target for incretin hormones?
(Elsevier Science Inc, 2015-12)
We tested the exendin-4 and des-fluoro-sitagliptin effects on fructose-induced increase in liver glucokinase activity in rats with impaired glucose tolerance and the exendin-4 effect on glucokinase activity in HepG2 cells ...
Regulation of Na(+)/H(+) exchanger NHE3 by glucagon-like peptide 1 receptor agonist exendin-4 in renal proximal tubule cells
(AMER PHYSIOLOGICAL SOC, 2009)
Carraro-Lacroix LR, Malnic G, Girardi AC. Regulation of Na(+)/H(+) exchanger NHE3 by glucagon-like peptide 1 receptor agonist exendin-4 in renal proximal tubule cells. Am J Physiol Renal Physiol 297: F1647-F1655, 2009. ...
The Food Environment, Preference, and Experience Modulate the Effects of Exendin-4 on Food Intake and Reward
(2017)
ObjectiveThe obesogenic food environment facilitates access to multiple palatable foods. Exendin-4 (EX4) is a glucagon-like peptide 1 receptor (GLP1R) agonist that inhibits food intake and has been proposed as an obesity ...
Sitagliptin prevents the development of metabolic and hormonal disturbances, increased β-cell apoptosis and liver steatosis induced by a fructose-rich diet in normal rats
(Portland Press, 2011-01)
The aim of the present study was to test the effect of sitagliptin and exendin-4 upon metabolic alterations, β-cell mass decrease and hepatic steatosis induced by F (fructose) in rats. Normal adult male Wistar rats received ...
Una formulación liofilizada para la preparación de Lys27(99MTc-EDDA/HYNIC)-Exendin(9-39)/99MTc-EDDA/HYNIC-TYR3-Octreótido para de-tectar insulinomas benignos y malignosUna formulación liofilizada para la preparación de Lys27(99MTc-EDDA/HYNIC)-Exendin(9-39)/99MTc-EDDA/HYNIC-TYR3-Octreótido para de-tectar insulinomas benignos y malignos
(Revista de Medicina e Investigación, Universalidad Autónoma del Estado de México, 2016)
Participação do Peptídeo semelhante ao Glucagon-1 (GLP-1) na modulação de mecanismos que regulam a massa de células β pancreáticas em ratas adultas submetidas à restrição proteica na vida intrauterina e lactação e recuperadas após o desmame
(Universidade Federal de Mato GrossoBrasilFaculdade de Nutrição (FANUT)UFMT CUC - CuiabáPrograma de Pós-Graduação em Nutrição, Alimentos e Metabolismo, 2019-02-20)
Protein restriction in early life reduces permanently the β-cell mass, due to increase of
apoptosis and reduction of proliferation. The glucagon-like peptide-1 (GLP-1) stimulates
the replication and neogenesis, and reduces ...
Drugs commonly associated with weight change: Umbrella systematic review and meta-analysis (Protocol)
(BioMed Central, 2012)
Background: Many drugs and treatments given to patients for various reasons affect their weight. This side effect is of great importance to patients and is also a concern for the treating physician because weight change ...