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Biotransformation of ent-beyerenes with mucor plumbeus
(Sociedad Chilena de Quimica, 2013)
ABSTRACT The microbiological transformation of ent-beyer-15-en-18-ol 1 and ent-beyer-15-en-19-ol 2, using Mucor plumbeus, resulted in hydroxylated products. After nine days of incubation, 15?,16?-epoxide-ent-beyeran-7b,18-diol ...
Gastroprotective activity of ent-beyerene derivatives in mice: Effects on gastric secretion, endogenous prostaglandins and non-protein sulfhydryls
(Elsevier, 2015)
Seventeen compounds (2-18) synthetized from the diterpenoid ent-beyer-15-en-18-ol (1) isolated from aerial part of Baccharis tola were tested for their gastroprotective activity on the model of HCl/EtOH-induced gastric ...
Estudio químico y Biológico de Perymenium buphthalmoides
(Universidad Michoacana de San Nicolás de Hidalgo, 2021-07)
The phytochemical analysis of the EtOAc extract of the flowers from Perymenium buphthalmoides afforded oleanyl palmitates (10) and oleanolic acid (11) as major constituents. As part of the chemical characterization, the ...
ent-Beyerane Diterpenes as a Key Platform for the Development of ArnT-Mediated Colistin Resistance Inhibitors
(American Chemical Society, 2020)
Colistin is a last-resort antibiotic for the treatment of multidrug resistant Gram-negative bacterial infections. Recently, a natural ent-beyerene diterpene was identified as a promising inhibitor of the enzyme responsible ...
ent-Beyerane Diterpenes as a Key Platform for the Development of ArnT-Mediated Colistin Resistance Inhibitors
(American Chemical Society, 2020)
Colistin is a last-resort antibiotic for the treatment of multidrug resistant Gram-negative bacterial infections. Recently, a natural ent-beyerene diterpene was identified as a promising inhibitor of the enzyme responsible ...
Structural elucidation and antimicrobial characterization of novel diterpenoids from Fabiana densa var. ramulosa
(American Chemical Society, 2020)
Novel diterpenoids were isolated from the extracts of Fabiana densa var. ramulosa and found to display a selective activity against Gram-positive bacterial strains with negligible cytotoxicity toward human keratinocytes. ...