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The Thiol-polyamine Metabolism of Trypanosoma cruzi: Molecular Targets and Drug Repurposing Strategies
(Bentham Science Publishers, 2018-09)
Chagas´ disease continues to be a challenging and neglected public health problem in many American countries. The etiologic agent, Trypanosoma cruzi, develops intracellularly in the mammalian host, which hinders treatment ...
Perfil dos usuários de medicamentos do componente especializado da assistência farmacêutica no município de São Leopoldo, RS
(Universidade do Vale do Rio dos Sinos, 2015-08-31)
The objective of this study was to describe the demographic and pharmacotherapeutic drug users’ profiles of the Specialized Component of Pharmaceutical Care (CEAF), and in addition, account expenses on the most prevalent ...
Perfil dos usuários de medicamentos do componente especializado da assistência farmacêutica no município de São Leopoldo, RS
(Universidade do Vale do Rio dos Sinos, 2015-08-31)
The objective of this study was to describe the demographic and pharmacotherapeutic drug users’ profiles of the Specialized Component of Pharmaceutical Care (CEAF), and in addition, account expenses on the most prevalent ...
Role of CC chemokines subfamily in the platinum drugs resistance promotion in cancer
(Frontiers Media, 2020)
Cancer is a significant medical issue, being one of the main causes of mortality around the world. The therapies for this pathology depend on the stage in which the cancer is found, but it is usually diagnosed at an advanced ...
Composite polymer-bioceramic scaffolds with drug delivery capability for bone tissue engineering
(Informa Healthcare, 2013-10)
Next-generation scaffolds for bone tissue engineering (BTE) should exhibit the appropriate combination of mechanical support and morphological guidance for cell proliferation and attachment while at the same time serving ...
Effect of chemotherapeutic drugs on telomere length and telomerase activity
(Smart Science & Technology, 2016-12)
Telomeres are specialized nucleoproteic complexes localized at the ends of eukaryotic chromosomes, that maintain their stability and integrity. They protect chromosome ends from fusion and from being recognized as sites ...
Profile of requests for high cost drugs to the Unified Health System in Minas Gerais, BrazilPerfil de solicitudes de medicamentos de alto costo en el Sistema Único de Salud en Minas GeraisPerfil das solicitações de medicamentos de alto custo ao Sistema Único de Saúde em Minas Gerais
(Escola Brasileira de Administração Pública e de Empresas da Fundação Getulio Vargas, 2014)
Avaliação da estabilidade de soluções químicas de trabalho atenolol por HPLC
(Universidade Tecnológica Federal do ParanáToledoBrasilAnálise InstrumentalUTFPR, 2019-06-06)
The bodily functioning depends on the good blood flow, which circulates several vital components and works integrally exerting some pressure on the blood vessels, which can be altered by several factors. Thus, hypertension, ...