Buscar
Mostrando ítems 1-10 de 376
The "first hit" toward alcohol reinforcement: Role of ethanol metabolites
(Blackwell Publishing Ltd, 2015)
Social defeat stress in rats: escalation of cocaine and speedball binge self-administration, but not heroin
(Springer, 2011-05-01)
Exposure to intermittent episodes of social defeat stress can increase drug seeking and leads to intense drug taking in rats.This study investigated the consequences of repeated, intermittent social defeat stress on patterns ...
Dorsal hippocampus plays a causal role in context-induced reinstatement of alcohol-seeking in rats
(2021-02-01)
Drug addiction is a chronic mental disorder characterized by frequent relapses. Contextual cues associated with drug use to play a critical causal role in drug-seeking behavior. The hippocampus has been implicated in ...
New Insights into the Mechanisms of Action of Cotinine and its Distinctive Effects from Nicotine
(Springer New York LLC, 2014)
Social defeat stress in rats: escalation of cocaine and speedball binge self-administration, but not heroin
(Springer, 2011-05-01)
Exposure to intermittent episodes of social defeat stress can increase drug seeking and leads to intense drug taking in rats.This study investigated the consequences of repeated, intermittent social defeat stress on patterns ...
Grupos terapéuticos
(Servicio Nacional de Aprendizaje (SENA), 2017)
Prenatal exposure to ethanol during late gestation facilitates operant self-administration of the drug in 5-day-old rats
(Elsevier Science Inc, 2014-02)
Prenatal ethanol exposure modifies postnatal affinity to the drug, increasing the probability of ethanol use and abuse. The present study tested developing rats (5-day-old) in a novel operant technique to assess the degree ...
Intranasal mesenchymal stem cell secretome administration markedly inhibits alcohol and nicotine self-administration and blocks relapse-intake: mechanism and translational options
(2019)
Background: Chronic consumption of most drugs of abuse leads to brain oxidative stress and neuroinflammation, which inhibit the glutamate transporter GLT-1, proposed to perpetuate drug intake. The present study aimed at ...
Relationship between ethanol and sucrose self-administration and schedule-induced polydipsia
(PERGAMON-ELSEVIER SCIENCE LTD, 2008)
Studies have suggested a relationship between drug abuse and compulsive behaviors. The present experiments investigated the relationship between schedule-induced polydipsia (SIP) and self-administration (SA) of ethanol and ...
Assessment of tolerance to the effects of methamphetamine on daytime and nighttime activity evaluated with actigraphy in rhesus monkeys
(Springer, 2017)
Methamphetamine is one of the most largely consumed illicit drugs, and its use is associated with abuse liability and several adverse health effects, such as sleep impairment. Importantly, sleep quality can influence ...