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The "first hit" toward alcohol reinforcement: Role of ethanol metabolites
(Blackwell Publishing Ltd, 2015)
The role of orexins/hypocretins in alcohol use and abuse: an appetitive-reward relationship
(Frontiers Research Foundation, 2012-11-22)
Orexins (hypocretins) are neuropeptides synthesized in neurons located in the lateral (LH), perifornical, and dorsomedial (DMH) hypothalamus. These neurons innervate many regions in the brain and modulate multiple other ...
Relationship Between Impulsivity, Sensation-Seeking, and Drug Use in Aggressors and Victims of Violence
(Frontiers Media S.A., 2020-10-30)
Introduction: The impulsivity, sensation-seeking, and drug use variables, in addition to being closely related, have repercussions on peer conflict and violence in schools. Objective: The purpose of this study was to analyze ...
Are reasons for the first use of drugs and family circumstances predictors of future use patterns?
(Elsevier B.V., 2002-01-01)
The objective of this study was to investigate whether the level of drug dependence in adolescents can be predicted by any of the following factors: the reasons to which the first use or non-use of drugs is attributed, ...
Dorsal hippocampus plays a causal role in context-induced reinstatement of alcohol-seeking in rats
(2021-02-01)
Drug addiction is a chronic mental disorder characterized by frequent relapses. Contextual cues associated with drug use to play a critical causal role in drug-seeking behavior. The hippocampus has been implicated in ...
Characterizing the syphilis epidemic among men who have sex with men in Lima, Peru to identify new treatment and control strategies
(BioMed Central, 2013)
Background: Syphilis is an important sexually transmitted infection (STI) with serious public health consequences. Among men who have sex with men (MSM) in Lima, the prevalence and incidence are extraordinarily high. Current ...
Functional inactivation of the orbitofrontal cortex disrupts context-induced reinstatement of alcohol seeking in rats
(Elsevier B.V., 2018-05-01)
Background: The high rate of relapse to drug use remains a central challenge to treating drug addiction. In human and rat models of addiction, environmental stimuli in contexts associated with previous drug use can provoke ...