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The "first hit" toward alcohol reinforcement: Role of ethanol metabolites
(Blackwell Publishing Ltd, 2015)
Ligand and structure-based modeling of passive diffusion through the blood-brain barrier
(Bentham Science Publishers B.V., 2018)
Post-treatment vascular leakage and inflammatory responses around brain cysts in porcine neurocysticercosis
(Public Library of Science, 2015)
Cysticidal treatment of neurocysticercosis, an infection of humans and pig brains with Taenia solium, results in an early inflammatory response directed to cysts causing seizures and focal neurological manifestations. ...
Nanoparticles as alternative strategies for drug delivery to the Alzheimer brain : Electron microscopy ultrastructural analysis
(2015-12-01)
One of the biggest problems and challenges for the development of new drugs and treatment strategies against Alzheimer Disease (AD) is the crossing of target drugs into the blood brain barrier. The use of nanoparticles in ...
Brain-to-Plasma Concentration Ratio and Unbound Partition Coefficient
(Springer Nature Switzerland AG, 2021)
The brain-to-plasma concentration ratio (or totalbrain-to-plasma ratio, or simply, brain-to-plasma ratio, Kp, also referred toas B/P ratio or BB) is, as suggested by the name, the ratio between the total(bound and unbound) ...
Acute and chronic elevation of erythropoietin in the brain improves exercise performance in mice without inducing erythropoiesis
(Wiley, 2012)
Application of recombinant human erythropoietin (rhEpo) improves exercise capacity by stimulating red blood cell production that, in turn, enhances oxygen delivery and utilization. Apart from this, when applied at high ...
Neonatal rat exposure to pyrethroid and organophosphate insecticides: A physiological and biochemical trial of progeny
(2004-10-14)
A manufactured product (Ectoplus®) composed by a cypermethrin (44.7%) and dichlorvos (4.2%) mixture was administered (10mg/kg/day, orally, by gavage) to pregnant rats, during the periods of gestation+lactation, gestation, ...
Neonatal rat exposure to pyrethroid and organophosphate insecticides: A physiological and biochemical trial of progeny
(2004-10-14)
A manufactured product (Ectoplus®) composed by a cypermethrin (44.7%) and dichlorvos (4.2%) mixture was administered (10mg/kg/day, orally, by gavage) to pregnant rats, during the periods of gestation+lactation, gestation, ...