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Two-dimensional transport analysis of transdermal drug absorption with a non-perfect sink boundary condition at the skin-capillary interface
(ELSEVIER SCIENCE INC, 2013-07-01)
A transient percutaneous drug absorption model was solved in two dimensions. Clearance of the topically-applied pharmaceutical occured at the skin-capillary boundary. Timolol penetration profiles in the dermal tissue were ...
Microemulsões: Estrutura e aplicações como sistema de liberação de fármacos
(2004-01-01)
Depending on formula composition, microemulsions may be used as a vehicle for drug administration. In this work the main applicable parameters used in the development of pharmaceutical microemulsions (ME) are analyzed. The ...
Microemulsões: Estrutura e aplicações como sistema de liberação de fármacos
(2004-01-01)
Depending on formula composition, microemulsions may be used as a vehicle for drug administration. In this work the main applicable parameters used in the development of pharmaceutical microemulsions (ME) are analyzed. The ...
Validation of UV spectrophotometric method for determination of lomefloxacin in pharmaceutical dosage form
(2005-07-01)
A simple and reproducible method was developed for the assay of lomefloxacin in tablets. The excipients in the commercial tablet preparation did not interfere with the assay. Beer's law is obeyed in the range 2.0-9.0 μg.mL-1 ...
Validation of UV spectrophotometric method for determination of lomefloxacin in pharmaceutical dosage form
(2005-07-01)
A simple and reproducible method was developed for the assay of lomefloxacin in tablets. The excipients in the commercial tablet preparation did not interfere with the assay. Beer's law is obeyed in the range 2.0-9.0 μg.mL-1 ...
Evaluation of skin absorption of drugs from topical and transdermal formulations
(Univ Sao Paulo, Conjunto Quimicas, 2016-07-01)
The skin barrier function has been attributed to the stratum corneum and represents a major challenge in clinical practice pertaining to cutaneous administration of drugs. Despite this, a large number of bioactive compounds ...