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Estudos sobre liberação controlada e vetorização de drogas através de lipossomas
The text highlights the state of research related with the application of liposomes in the control of drug delivery and drug target to infectious diseases. Liposomes have several pharmaceutical applications and this ...
Sistemas para liberação colônica: Uma alternativa para a veiculação de fármacos para efeito local ou sistêmico
Problems related to the systemic administration of drugs, such as biodistribution, difficulty of targeting, necessity of high doses to achieve adequate levels of the drug in specific sites, toxicity, and undesirable side ...
Gold nanoparticles for photothermally controlled drug release
(Future Medicine Ltd., 2014)
© 2014 Future Medicine Ltd. In this article, we describe how nanoparticles work in photothermally triggered drug delivery, starting with a description of the plasmon resonance and the photothermal effect, and how this is ...
Estratégias biotecnológicas para a liberação controlada de antígenos e adjuvantes em vacinas através de lipossomas
Liposomes (LP) are colloidal systems with ability to compartmentalize therapeutic molecules in order to improve biological activity, decreases the potential toxicity, and to obtain prolonged effect. In this work it was ...
Understanding Drug Release Data through Thermodynamic Analysis
(Mdpi Ag, 2017-06-01)
Understanding the factors that can modify the drug release profile of a drug from a Drug-Delivery-System (DDS) is a mandatory step to determine the effectiveness of new therapies. The aim of this study was to assess the ...
Multiparticulate systems of pectin-chitosan: Study of swelling and drug release
The aim of this study was to prepare multiparticulate systems of pectin:chitosan (PC:CS) and to evaluate their swelling ratio and the drug release in different environments. PC:CS particles containing triamcinolone were ...
Preparation and characterization of poly(ε-caprolactone) nanospheres containing the local anesthetic lidocaine
The objective of this work was to develop a modified release system for the local anesthetic lidocaine (LDC), using poly(ε-caprolactone) (PCL) nanospheres (NSs), to improve the pharmacological properties of the drug when ...
Preparation and characterization of poly(e-caprolactone) nanospheres containing the local anesthetic lidocaine
LC Evaluation of In Vitro Release of AZT from Microemulsions
A reversed phase LC method was developed and validated to analyze the in vitro release of AZT from microemulsions. A mobile phase of acetonitrile:water (15:85) was used. The method validation showed good selectivity and ...