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Cholinesterase inhibitors for Alzheimer's disease: Multitargeting strategy based on anti-Alzheimer's drugs repositioning
(Bentham Science Publishers, 2019)
Effects of donepezil on behavioral manifestations of thalamic infarction: A single-case observation
(2011)
Objective: To examine the effect of donepezil for the treatment of cognitive and behavioral disorders associated with thalamic lesions in a 45-year-old male who suffered an infarct in the left thalamus. Background: Recent ...
Estudos visando a síntese total da (±)-galantamina e síntese de híbridos donepezil-ácido lipóico
(Universidade Federal de Minas GeraisUFMG, 2017-11-29)
Alzheimer's disease (AD) is a neurodegenerative pathogenesischaracterized by cognitive impairment in patients, such as short-term memory impairment, speech and language loss, impaired motor coordination, and patient learning ...
Effects of donepezil on behavioral manifestations of thalamic infarction: A single-case observation
(Facultad de Ciencias, 2011)
Objective: To examine the effect of donepezil for the treatment of cognitive and behavioral disorders associated with thalamic lesions in a 45-year-old male who suffered an infarct in the left thalamus. Background: Recent ...
Benzodiazepines and Related Drugs as a Risk Factor in Alzheimer's Disease Dementia
(Frontiers Media S.A., 2020)
Neuroproteção do cassis (Ribes nigrum L.) e de sua associação com o Donepezil em modelo de amnésia induzida por escopolamina
(Universidade Federal de Santa MariaBrasilBioquímicaUFSMPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica ToxicológicaCentro de Ciências Naturais e Exatas, 2019-12-13)
Memory deficits that occur with the process of aging could also be associated with the pathophysiology of neurodegenerative diseases, such as Alzheimer’s disease (AD). AD is characterized by the progressive deterioration ...
Determinación en membranas celulares y modelos moleculares del efecto protector de drogas utilizadas en la enfermedad de Alzheimer.Determination in cell membranes and molecular models of the protective effect of drugs used in Alzheimer's disease.
(2019)
El péptido beta amiloide (Aβ) es tóxico para las neuronas. Desde hace más de una década se han examinado los efectos de medicamentos que tienen una acción inhibidora de la acetilcolinesterasa, con lo cual se han mejorado ...
Estudos computacionais e sintéticos visando o planejamento racional de novos agentes anticolinesterásicos
(Universidade Estadual Paulista (Unesp), 2010-08-13)
O presente trabalho teve como objetivo o planejamento e síntese de novas substâncias inibidoras da acetilcolinesterase, enzima cuja modulação está associada ao tratamento de diversas patologias, entre elas a doença de ...