A disulfiram suspension (propylenglycol and water) was used to treat 45 alcoholic patients. Inactive suspension was given to 8 control alcoholic patients. Pain, local inflammation, thirst and drowsiness were related to ...

The disposition of disulfiram after administration in a new formulation was studied in rats and alcoholic patients. The suspension consisted of microcrystals suspended in a mixture of propylene glycol and water and injected ...

Motles, Elias, Montserrat Tetas, Ariel Gomez, Claudio Briones and Magali Gonzalez: Effects of Disulfiram, Phenoxybenzamine and Propranolol on the Behaviors Evoked by Apomorphine and Amphetamine in Adult Cats. Prog. Neuro ...

Despite the fact that alcoholism is a severe public health problem of worldwide proportions, only a limited number of medications is used as coadjuvant treatment. the objectives of this study were to analyse the use of ...

Acetaldehyde (AcH) levels in blood samples taken from different zones of the vascular system 2 h after a p.o. dose of ethanol (2.76 g/kg) were studied in UChA (low ethanol consumer) and UChB (high ethanol consumer) rats ...

El alcoholismo y los efectos asociados a la ingesta de alcohol son el más importante problema de Salud Pública en Chile. El disulfiram es un fármaco utilizado en el tratamiento del alcoholismo crónico ya que produce una ...

Background: Disulfiram, an inhibitor of aldehyde dehydrogenase used in the treatment of alcoholism, is an effective medication when its intake is supervised by a third person. However, its therapeutic efficacy varies ...