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Brown spider dermonecrotic toxin directly induces nephrotoxicity
(Elsevier B.V., 2006-02-15)
Brown spider (Loxosceles genus) venom can induce dermonecrotic lesions at the bite site and systemic manifestations including fever, vomiting, convulsions, disseminated intravascular coagulation, hemolytic anemia and acute ...
Phospholipase-D activity and inflammatory response induced by brown spider dermonecrotic toxin: Endothelial cell membrane phospholipids as targets for toxicity
(Elsevier B.V., 2011-02-01)
Brown spider dermonecrotic toxins (phospholipases-D) are the most well-characterized biochemical constituents of Loxosceles spp. venom. Recombinant forms are capable of reproducing most cutaneous and systemic manifestations ...
Two novel dermonecrotic toxins LiRecDT4 and LiRecDT5 from Brown spider (Loxosceles intermedia) venom: From cloning to functional characterization
(Elsevier B.V., 2007-03-01)
Loxoscelism (the condition produced by the bite of brown spiders) has been reported worldwide, but especially in warmer regions. Clinical manifestations include skin necrosis with gravitational spreading while systemic ...
Necrotic skin lesion in a dog attributed to Loxosceles (brown spider) bite: a case report
(Universidade Estadual Paulista (Unesp), Centro de Estudos de Venenos e Animais Peçonhentos (CEVAP), 2009-01-01)
Envenomations caused by Loxosceles (brown spider) have been reported throughout the world. Clinical signs associated to bites of these spiders involve dermonecrotic lesions and intense local inflammatory response, besides ...
Necrotic skin lesion in a dog attributed to Loxosceles (brown spider) bite: a case report
(Universidade Estadual Paulista (Unesp), Centro de Estudos de Venenos e Animais Peçonhentos (CEVAP), 2009-01-01)
Envenomations caused by Loxosceles (brown spider) have been reported throughout the world. Clinical signs associated to bites of these spiders involve dermonecrotic lesions and intense local inflammatory response, besides ...
Necrotic skin lesion in a dog attributed to Loxosceles (brown spider) bite: A case report
(2009-10-12)
Envenomations caused by Loxosceles (brown spider) have been reported throughout the world. Clinical signs associated to bites of these spiders involve dermonecrotic lesions and intense local inflammatory response, besides ...
Necrotic skin lesion in a dog attributed to Loxosceles (brown spider) bite: a case report
(Universidade Estadual Paulista (UNESP), Centro de Estudos de Venenos e Animais Peçonhentos (CEVAP), 2014)
Nephrotoxicity caused by brown spider venom phospholipase-D (dermonecrotic toxin) depends on catalytic activity
(Elsevier B.V., 2008-11-01)
Bites from brown spiders (Loxosceles genus) have clinical manifestations including skin necrosis with gravitational spreading, and systemic involvement that may include renal failure, hemolysis, and thrombocytopenia. Mice ...
Identification of New Sphingomyelinases D in Pathogenic Fungi and Other Pathogenic Organisms
(Public Library ScienceSan FranciscoEUA, 2013)
An alternative method for purifying and detoxifying diphtheria toxin
(PERGAMON-ELSEVIER SCIENCE LTD, 2011)
Infections caused by Corynebacterium diphtheriae frequently induce situations in which very small doses of antigens injected intradermally can cause strong inflammatory reactions. This bacterium secretes the diphtheria ...